| 2010-09-08 |
700310 |
Free Fatty Acid Assay Kit
A sensitive tool for measuring free fatty acids in plasma, serum, and urine
The measurement of FFA can be useful in determining metabolic status. Cayman’s Free Fatty Acid (FFA) Assay provides a simple, reproducible, and sensitive tool for measuring free fatty acids in plasma, serum, and urine. The FFA Assay utilizes a coupled enzymatic reaction that results in generation of the highly fluorescent product resorufin. |
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0E-12
|
free-fatty-acid-assay-kit
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FFA
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kits assays measures measurements acids triglycerides intestines hydrolyzed glycerols enzymes pancreas pancreatic lipases intestinal liposomes capillaries lymph systems blood plasmas serums hepatocytes adipocytes muscles fibers oxidized sugars glucagon fats proteins albumin FFA skeletal skeletons hearts livers pathophysiological obesity insulin resistance type 2 II diabetes pathogenesis insulin-stimulated peripheral glucose uptake beta cells oxidative stressproinflammatory effects NFκB nuclear factors inflammation resistances metabolic urine enzymatic reactions Acyl CoA synthetase ACS acylation coenzymes oxidases ACOD hydrogen peroxides H2O2 horseradish peroxidases HRP 10-aceyl-3,7-dihydroxyphenozazine ADHP fluorescence fluorescent resorufins |
| 2010-09-07 |
13911 |
Caspase-3 Monoclonal Antibody (Clone 31A893)
For immunochemical analysis of caspase-3
Antigen:
recombinant full-length human caspase-3
·
Clone designation:
31A893
·
Host:
mouse
·
Application(s):
WB
·
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300.437306629834
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caspase-3-monoclonal-antibody-clone-31a893
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Yama; ICE3; CPP32; Apopain
|
caspases caspase 3 cysteine proteases cell death apoptosis antibodies western blots blotting immunoblotting WB immunohistochemistry IHC frozen paraffin-embedded paraffin embedded yama CPP32 apopain codes PARP poly(ADP-ribose) polymerase DNA-PK DNAPK DNA PK actin GAS2 pro-caspase procaspase pro CrmA small large subunits |
| 2010-09-07 |
13550 |
eIF4B Polyclonal Antibody (aa 150-200)
For immunochemical analysis of eIF4B
Antigen:
synthetic peptide from human eIF4B within the region of amino acids 150-200
·
Host:
rabbit
·
Application(s):
WB
·
Peptide sequence:
amino acids 150-200
·
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0E-12
|
eif4b-polyclonal-antibody-aa-150-200
|
Eukarytoic Translation Initiation Factor-4B
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antibodies eIF eukarytoic translation initiations factors RNA RRM recognition domains RNP-CS N-terminal N-terminus DRYG aspartic acids argine tyrosine glycine DEAD box inhibitory inhibition inhibits western blots immunoblotting WB mRNAs |
| 2010-09-07 |
10264 |
Histone H4 (human recombinant)
Peptide sequence:
Amino acids 1-103, full-length
·
Source:
recombinant protein, expressed in E. coli
·
Mr:
11.5 kDa
·
|
| 50 µg | $24.00 |
| 100 µg | $46.00 |
| 250 µg | $108.00 |
| 1 mg | $384.00 |
|
|
>95%
|
|
|
0E-12
|
histone-h4-human-recombinant
|
H4/p; MGC24116; HIST4H4
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|
| 2010-09-03 |
13549 |
eIF4A2 Polyclonal Antibody (aa 50-100)
For immunochemical analysis of eIF4A2
Antigen:
synthetic peptide from human eIF4A2 within the region of amino acids 50-100
·
Host:
rabbit
·
Application(s):
WB
·
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0E-12
|
eif4a2-polyclonal-antibody-aa-50-100
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Eukaryotic Translation Initiation Factor-4A2
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antibodies western blots blotting immunoblotting WB RNA DEAD box helicase eIF4F kinase MNK1 eIF4B eIF4G eIF4E PABC1 eIF4A1 mRNAs 40S ribosomal tissues |
| 2010-09-01 |
700420 |
Ascorbate Assay Kit
A fluorescence-based tool for quantifying ascorbate from plasma, serum, urine, and fruit juices
Ascorbate (L-Ascorbic acid or Vitamin C) is a six-carbon lactone that is synthesized from glucose in the liver of most mammalian species, but not by humans. Therefore, humans must obtain ascorbate in their diet in order to survive. In humans, ascorbate acts as an electron donor for eight different enzymes. It also serves as an antioxidant and may be beneficial for reducing the risk of developing chronic diseases such as cancer, cardiovascular disease, and cataracts. Cayman’s Ascorbate Assay provides a reproducible, sensitive fluorescence-based tool for quantifying ascorbate from plasma, serum, urine, and fruit juices. |
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0E-12
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ascorbate-assay-kit
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L-Ascorbic Acid Assay Kit; Vitamin C Assay Kit
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kits assays measures measurements ascorbates six-carbon 6-carbon six 6 carbons lactones glucose livers mammalian species humans non-human primates guinea pigs gulonolactones oxidases acids 2-keto-1-gulonolactone diets dietary scurvy electrons donors enzymes collagen hydroxylations hydroxyls groups prolines lysines molecules carnitines fatty mitochondrias ATP adenosine triphosphates generations biosynthesis norepinephrines dopamines amides groups peptides hormones tyrosines metabolisms antioxidants chronics diseases cancers cardiovascular cataracts foods industry colors tastes odors plasmas serums urines fruits juices condensations reactions dehydroascorbic DHA o-phenylenediamines OPDA fluorescent fluorescences 4-hydroxy-2,2,6,6-tetramethylpiperidinyloxy TEMPOL condensed DFQ 3-(dihydroxyethyl)-furo[34-b]-quinoxaline-1-one OPD |
| 2010-09-01 |
9000851 |
JWH 018 4-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 018 4-hydroxyindole metabolite is a major monohydroxylated urinary metabolite of JWH 018, a WIN 55,212-2 derivative that is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor. In urine samples, this metabolite is almost completely glucuronidated. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
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≥98%
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|
✓ |
0E-12
|
jwh-018-4-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 WIN55212-2 WIN 552122 WIN552122 WIN 55,2122 WIN55,2122 CB1 CB2 cannabimimetics urine urinary metabolites 1 glucuroconjugate forensics JWH-018 JWH018 209414-07-3 JWH018-metabolite JWH 018-metabolite one CBs M-1 M1 smoking mixtures spices |
| 2010-09-01 |
9000852 |
JWH 018 5-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 018 5-hydroxyindole metabolite is a major monohydroxylated urinary metabolite of JWH 018, a WIN 55,212-2 derivative that is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor. In urine samples, this metabolite is almost completely glucuronidated. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥98%
|
|
✓ |
0E-12
|
jwh-018-5-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 WIN55212-2 WIN 552122 WIN552122 WIN 55,2122 WIN55,2122 CB1 CB2 cannabimimetics urine urinary metabolite glucuroconjugate forensics JWH-018 JWH018 209414-07-3 foresnsic science pain nueroscience JWH-018-metabolite JWH018-metabolite JWH 018-metabolite two 2 smoking mixtures spices CBS M-2 M2 |
| 2010-09-01 |
9000853 |
JWH 018 6-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 018 6-hydroxyindole metabolite is a minor monohydroxylated urinary metabolite of JWH 018, a WIN 55,212-2 derivative that is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
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|
|
|
✓ |
0E-12
|
jwh-018-6-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 WIN55212-2 WIN 552122 WIN552122 WIN 55,2122 WIN55,2122 CB1 CB2 cannabimimetics urine urinary metabolites glucuroconjugate forensics JWH-018 JWH018 209414-07-3 foresnsic science pain nueroscience JWH-018-metabolite JWH018-metabolite JWH 018-metabolite three 3 M-3 M3 CBs smoking mixture spices |
| 2010-09-01 |
9000854 |
JWH 018 7-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 018 7-hydroxyindole metabolite is a minor monohydroxylated urinary metabolite of JWH 018, a WIN 55,212-2 derivative that is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥98%
|
|
✓ |
0E-12
|
jwh-018-7-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 WIN55212-2 WIN 552122 WIN552122 WIN 55,2122 WIN55,2122 CB1 CB2 cannabimimetics urine urinary metabolite glucuroconjugate forensics JWH-018 JWH018 209414-07-3 foresnsic science pain nueroscience JWH-018-metabolite JWH018-metabolite JWH 018-metabolite four 4 M4 M-4 smoking mixtures spices |
| 2010-09-01 |
9000855 |
JWH 018 N-(5-hydroxypentyl) metabolite
Urinary metabolite of synthetic cannabinoid JWH 018
JWH 018 metabolite 5 is a major urinary metabolite of JWH 018, characterized by monohydroxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
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≥98%
|
|
✓ |
0E-12
|
jwh-018-n-5-hydroxypentyl-metabolite
|
|
cannabinoids receptors WIN 55,212-2 WIN55212-2 WIN 552122 WIN552122 WIN 55,2122 WIN55,2122 CB1 CB2 cannabimimetics urine urinary metabolite glucuroconjugate forensics JWH-018 JWH018 209414-07-3 foresnsic science pain nueroscience JWH-018-metabolite JWH018-metabolite JWH 018-metabolite five 5 CBs M-5 M5 smoking mixtures spices |
| 2010-09-01 |
9000856 |
JWH 018 N-pentanoic acid metabolite
Urinary metabolite of synthetic cannabinoid JWH 018
JWH 018 Metabolite 6 is a minor urinary metabolite of JWH 018, characterized by carboxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
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≥98%
|
|
✓ |
0E-12
|
jwh-018-n-pentanoic-acid-metabolite
|
|
cannabinoids receptors WIN 55,212-2 WIN55212-2 WIN 552122 WIN552122 WIN 55,2122 WIN55,2122 CB1 CB2 cannabimimetics urine urinary metabolite glucuroconjugate forensics JWH-018 JWH018 209414-07-3 science pain nueroscience JWH-018-metabolite JWH018-metabolite JWH 018-metabolite 6 six CBs M6 M-6 smoking mixtures spices |
| 2010-09-01 |
9000861 |
JWH 073 4-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 073 4-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥98%
|
|
✓ |
0E-12
|
jwh-073-4-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 CB1 CB2 cannabimimetics urine urinary metabolites forensics JWH 073 Metabolite 1 JWH-073 JWH073 M-1 CBs smoking mixtures spices |
| 2010-09-01 |
9000862 |
JWH 073 5-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 073 5-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥98%
|
|
✓ |
0E-12
|
jwh-073-5-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 CB1 CB2 cannabimimetics urine urinary metabolites glucuroconjugate forensics JWH 073 Metabolite 2 JWH-073 JWH073 CBs M-2 agonists smoking mixtures spices |
| 2010-09-01 |
9000863 |
JWH 073 6-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 073 6-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥95%
|
|
✓ |
0E-12
|
jwh-073-6-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 CB1 CB2 cannabimimetics urine urinary metabolites forensics JWH 073 Metabolite 3 JWH-073 JWH073 M-3 CBs smoking mixtures spices |
| 2010-09-01 |
9000864 |
JWH 073 7-hydroxyindole metabolite
A synthetic cannabinoid urinary metabolite
JWH 073 7-hydroxyindole metabolite, is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
98%
|
|
✓ |
0E-12
|
jwh-073-7-hydroxyindole-metabolite
|
|
cannabinoids receptors WIN 55,212-2 CB1 CB2 cannabimimetics urine urinary metabolites forensics JWH 073 Metabolite 4 JWH-073 CBs JWH073 M-4 mixtures smoking spices |
| 2010-09-01 |
9000865 |
JWH 073 N-(5-hydroxybutyl) metabolite
Urinary metabolite of synthetic cannabinoid JWH 073
JWH 073 N-(5-hydroxybutyl) metabolite is expected to be a major urinary metabolite of JWH 073, characterized by monohydroxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018. In urine samples, this metabolite of JWH 018 is almost completely glucuronidated. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥98%
|
|
✓ |
0E-12
|
jwh-073-n-5-hydroxybutyl-metabolite
|
|
cannabinoids receptors WIN 55,212-2 CB1 CB2 cannabimimetics urine urinary metabolites glucuroconjugate forensics JWH 073 Metabolite 5 JWH-073 smoking JWH073 CBs mixtures spices M-5 |
| 2010-09-01 |
9000866 |
JWH 073 N-butanoic acid metabolite
Urinary metabolite of synthetic cannabinoid JWH 073
JWH 073 N-butanoic acid metabolite is expected to be a urinary metabolite of JWH 073, characterized by carboxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018. In urine samples, this metabolite of JWH 018 is almost completely glucuronidated. |
| 1 mg | $110.00 |
| 5 mg | $495.00 |
| 10 mg | $880.00 |
| 50 mg | $3,850.00 |
|
|
≥98%
|
|
✓ |
0E-12
|
jwh-073-n-butanoic-acid-metabolite
|
|
cannabinoids receptors WIN 55,212-2 CB1 CB2 cannabimimetics urine urinary metabolites glucuroconjugates forensics JWH 073 Metabolite 6 JWH-073 CBs JWH073 M-6 smoking mixtures spices |
| 2010-08-31 |
13548 |
eIF4A2 Polyclonal Antibody (aa 1-50)
For immunochemical analysis of eIF4A2
Antigen:
synthetic peptide from human eIF4A2 within the region of amino acids 1-50
·
Host:
rabbit
·
Application(s):
IHC (paraffin embedded-sections) and WB
·
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|
|
0E-12
|
eif4a2-polyclonal-antibody-aa-1-50
|
Eukaryotic Translation Initiation Factor-4A2
|
antibodies western blots blotting immunoblotting WB RNA DEAD box helicase eIF4F kinase MNK1 eIF4B eIF4G eIF4E PABC1 eIF4A1 mRNAs 40S ribosomal tissues immunohistochemistry IHC |
| 2010-08-30 |
500390 |
Cysteinyl Leukotriene EIA Kit
A competitive assay used for quantification of CysLT
Limit of detection:
80% B/B0: 34 pg/ml
·
Sensitivity:
50% B/B0: 103 pg/ml
·
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid via the 5-lipoxygenase (5-LO) pathway in leukocytes. LTC4, LTD4, and LTE4 are collectively referred to as cysteinyl leukotrienes (CysLTs). LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. The biological activity of LTE4 is much lower in most systems studied, but its presence reflects the prior existence of LTC4 and LTD4. Cayman’s CysLT EIA Kit is a competitive assay based on a proprietary high-affinity monoclonal antibody that can be used for quantification of CysLT in urine and other sample matrices. The EIA typically displays an IC50 (50% B/B0) of approximately 103 pg/ml and a detection limit (80% B/B0) of approximately 34 pg/ml. |
| 96 solid wells | $336.00 |
| 96 strip wells | $336.00 |
| 480 solid wells | $1,260.00 |
| 480 strip wells | $1,260.00 |
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|
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0E-12
|
cysteinyl-leukotriene-eia-kit
|
CysLT ELISA Kit
|
cys LTs solid plates leukotrienes CysLTs acute inflammatory mediators arachidonic acids leukocytes 5-LO lipoxygenases bone marrow cells eosinophils mast macrophages LTA4 LTC4 LTD4 LTE4 human lungs mediators asthma hypersensitivity bronchoconstriction microvascular permeability vasoconstrictors coronary arteries competitive assays kits quantification urine culture media sample matrix matrices enzymes immuno ELISAs |
| 2010-08-30 |
9000432 |
Oleic Acid-d17
An internal standard for the quantification of oleic acid
Oleic acid-d17 contains 17 deuterium atoms at the 11, 11’, 12, 12’, 13, 13’, 14, 14’, 15, 15’, 16, 16’, 17, 17’, 18, 18, and 18 positions. It is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-mass spectrometry. |
| 1 mg | $85.00 |
| 5 mg | $383.00 |
| 10 mg | $680.00 |
| 50 mg | $2,975.00 |
|
|
≥99% deuterated product
|
|
|
0E-12
|
oleic-acid-d17
|
|
deuterium internal isotopes GC/MS GC-MS LC/MS LC-MS mass spectrometry deuterated fatty acids monounsaturated 9Z-octadecenoic |
| 2010-08-30 |
700320 |
Uric Acid Assay Kit
A fluorescence-based method for detecting uric acid in serum, plasma, and urine
Uric acid (urate) is the end product of human purine metabolism and is mainly excreted in urine. Many factors, including genetic components and acquired factors, such as obesity and alcohol consumption, influence serum uric acid concentrations. Hyperuricemia induces or facilitates gout, kidney stones, metabolic syndrome, hypertension, and renal and cardiovascular disease, while exercise-induced acute renal failure is a significant complication of renal hypouricemia. Cayman’s Uric Acid Assay provides a fluorescence-based method for detecting uric acid in serum, plasma, and urine. |
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0E-12
|
uric-acid-assay-kit
|
Urate Assay Kit
|
kits assays measures measurement acids human purines metabolisms urine serum renal excretion excreted allantoin enzymes urate oxidases uricase genes obesity alcohol consumption hyperuricemia gout kidney stones metabolic syndromes hypertension cardiovascular diseases exercise-induced acute failure hypouricemia |
| 2010-08-23 |
13838 |
CAY10626
A dual PI3Kα/mTOR kinase inhibitor
CAY10626 is a potent, dual PI3Kα/mTOR inhibitor with IC50 values of 0.9 and 0.6 nM for the two respective kinases. In a tumor cell growth inhibition assay, CAY10626 demonstrates IC50 values of <3 and 13 nM for MDA361 (breast) and PC3 (prostate) cancer cell lines, respectively. When administered at 25-50 mg/k to MD361 xenograft mice, phosphorylation of the downstream targets of PI3Kα and mTOR (Akt T308, Akt S473, and S6K) was suppressed, and significant tumor regression was observed. |
| 1 mg | $82.00 |
| 5 mg | $369.00 |
| 10 mg | $656.00 |
| 25 mg | $1,435.00 |
|
1202884-94-3 |
≥98%
|
|
✓ |
0E-12
|
cay10626
|
|
PI3Kα mTOR cancers signal transduction inhibitors inhibits inhibition phosphatidylinositol 3-kinase PtdIns PIs |
| 2010-08-23 |
9000595 |
CEP-Lysine-d4
A deuterated form of CEP-lysine
CEP-Lysined4 contains four deuterium atoms at the carboxyethyl 1,1',2,2' positions. It is intended for use as an internal standard for the quantification of CEP-lysine by GC- or LC-mass spectrometry (MS). |
| 500 µg | $165.00 |
| 1 mg | $314.00 |
| 5 mg | $1,320.00 |
| 10 mg | $2,310.00 |
|
|
≥99% deuterated product
|
|
✓ |
0E-12
|
cep-lysine-d4
|
|
Docosahexaenoic acid DHA oxidative stress 2-(ω-carboxyethyl)pyrrole CEP carboxyethylpyrrole advanced glycation end products biomarkers age-related macular degeneration deuterateds internal standard GC LC chromatography mass spectrometry GC-MS LC-MS GC/MS LC/MS deuterium |
| 2010-08-23 |
10461 |
Paclitaxel
A potent mitotic inhibitor
Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values ranging from 2.5-7.5 nM. Paclitaxel disrupts multipolar spindle formation, inducing cell cycle arrest in various human cell cancer lines (IC50s = 6.7-18.5 nM) at both prophase and G1. It initiates apoptosis of cancer cells through multiple mechanisms involving p53-dependent and -independent pathways, Bcl-2 family members, cyclin-dependent kinases, and c-Jun N-terminal kinases/stress-activated protein kinases. |
| 5 mg | $18.00 |
| 25 mg | $81.00 |
| 50 mg | $144.00 |
| 100 mg | $288.00 |
|
33069-62-4 |
≥98%
|
|
|
0E-12
|
paclitaxel
|
Taxol®; NSC 125973
|
Microtubules cancers cervical HeLa lung A549 breast MCF-7 colon HT-29 ovarian OVG-1 pancreatic PC-Sh carcinomas chemotherapy mitotic arrest apoptosis JNK BCL-2 p53 Pacific yew tree c-Jun cyclin-dependent kinases multipolar spindle formation Abraxane Capxol Mitotax Onxal QW 8184 Yewtaxan Tocosol Taxus Liberte Genexol-PM Genetaxyl EndoTAG 1 Ebetaxwl DHP 107 ABI 007 |