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Primary Eicosanoid HPLC Mixture

Cayman Chemical Item Number 10001

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Description

This mixture contains the primary COX products produced by most mammalian tissues. Contents: Prostaglandin D2, Prostaglandin E2, 6-keto Prostaglandin F, Prostaglandin F, and Thromboxane B2 (100 µg each).
Formulation A solution in methyl acetate
Purity >98% for each compound
Stability 6 months
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Salmon, J.A., and Flower, R.J. Extraction and thin-layer chromatography of arachidonic acid metabolites. Methods Enzymol 86 477-493 (1982).

Fournier, T., Fadok, V., and Henson, P.M. Tumor necrosis factor-α inversely regulates prostaglandin D2 and prostaglandin E2 production in murine macrophages. Synergistic action of cyclic AMP on cyclooxygenase-2 expression and prostaglandin E2 synthesis. J Biol Chem 272 31065-31072 (1997).

Salari, H., Yeung, M., Douglas, S., et al. Detection of prostaglandins by high-performance liquid chromatography after conversion to p-(9-anthroyloxy)phenacyl esters. Anal Biochem 165 220-229 (1987).

Powell, W.S. Reversed-phase high-pressure liquid chromatography of arachidonic acid metabolites formed by cyclooxygenase and lipoxygenases. Anal Biochem 148 59-69 (1985).

Watanabe, K., Kurihara, K., Tokunaga, Y., et al. Two types of microsomal prostaglandin E synthase: Glutathione-dependent and -independent prostaglandin E synthases. Biochem Biophys Res Commun 235 148-152 (1997).

Castagnoli, M., Bellucci, S., Maclouf, J., et al. Combined high-performance liquid chromatography and enzyme immunoassay for the determination of urinary metabolites of thromboxane and 6-keto-PGF. Adv Prostaglandin Thromboxane Leukot Res 17 603-607 (1987).

Hamberg, M., Svensson, J., and Samuelsson, B. Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 72 2994-2998 (1975).

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Size Price Quantity Subtotal
1 ea $61.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

6-keto Prostaglandin F
Cyclopentenone Prostaglandin HPLC Mixture
Prostaglandin D2
Prostaglandin E2
Prostaglandin F
Prostaglandin HPLC Mixture
Prostaglandin Metabolite HPLC Mixture
Thromboxane B2
Vasoactive Eicosanoid HPLC Mixture
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