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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

CD4 Monoclonal Antibody (Clone RIV7)

Cayman Chemical Item Number 10004599

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Description

Clone designation: RIV7 · Host: mouse · Isotype: IgG2a · Application(s): (+) immunocytochemistry, immunohistochemistry (frozen tissue sections), and flow cytometry; (−) western blot and immunohistochemistry (paraffin-embedded tissue sections) · CD4 is a transmembrane glycoprotein present on the surface of a majority of thymocytes and T cell subpopulations, which recognize antigens presented by MHC class II molecules. The CD4 antigen is also found on monocytes, dendritic cells, tissue macrophages, and granulocytes. CD4+ T lymphocytes are presented by functional T-helper cells and CD4+CD25+ regulatory (suppressor) T cells. Estimation of CD4+ T cell level could be used for immunological status monitoring.1

1 Jonker, M., Nooij, F.J.M., Den Butter, G., et al. Side effects and immunogenicity of murine lymphocyte-specific monoclonal antibodies in subhuman primates. Transplantation 45(4) 677-682 (1988).

Formulation 100 µg protein-A purified IgG2a in 500 µl PBS, pH 7.2, containing 0.02% sodium azide
Stability 1 year
Storage 4°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human CD4 +

Background Reading

Jonker, M., Nooij, F.J.M., Den Butter, G., et al. Side effects and immunogenicity of murine lymphocyte-specific monoclonal antibodies in subhuman primates. Transplantation 45(4) 677-682 (1988).
Size Price Quantity Subtotal
1 ea $229.00 $0.00
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Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

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