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10005032 5(S),6(R)-7-trihydroxymethyl Heptanoate
BML-111
5(S),6(R)-7-trihydroxymethyl Heptanoate Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Lipoxins are trihydroxytetraene metabolites derived from arachidonic acid through an interaction between lipoxygenases with C-5 and C-15 specificities. Lipoxin A4 (LXA4) inhibits the chemotactic responsiveness of polymorphonuclear (PMN) neutrophils to leukotriene B4 and to the peptide formyl-methionyl-leucyl-phenylalanine (fMLP).1 5(S),6(R)-7-trihydroxymethyl heptanoate is a C-7 truncated analog of LXA4 that is equiactive as LXA4 in the inhibition of LTB4-induced PMN chemotaxis with an IC50 of 5nM.1
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1
Lee, T.H., Lympany, P., Crea, A.E.G., et al. Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: Structure-function relationships. Biochem Biophys Res Commun 180(3) 1416-1421 (1991).
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Purchase 10005032 5(S),6(R)-7-trihydroxymethyl Heptanoate
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-19.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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