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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

ACAT-1 Blocking Peptide

Cayman Chemical Item Number 10005090

Sterol O-Acyltransferase 1; Cholesterol Acyltransferase 1; Acyl-coenzyme A:Cholesterol Acyltransferase-1

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Description

Peptide sequence: human ACAT-1 amino acids 6-23 · To be used in conjunction with Cayman’s ACAT-1 polyclonal antibody (Catalog No. 100028) to block protein-antibody complex formation during immunochemical analysis for ACAT-1.
Synonyms
  • Sterol O-Acyltransferase 1
  • Cholesterol Acyltransferase 1
  • Acyl-coenzyme A:Cholesterol Acyltransferase-1
Formulation 200 µg of peptide in 200 µl TBS, pH 7.4, containing 0.1% BSA and 0.02% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Rudel, L.L., Lee, R.G., and Cockman, T.L. Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr Opin Lipidol 12 121-127 (2001).

Linton, M.F., and Fazio, S. Macrophages, inflammation, and atherosclerosis. Int J Obes 27 S35-S40 (2003).

Namatame, I., Tomoda, H., Ishibashi, S., et al. Antiatherogenic activity of fungal beauveriolides, inhibitors of lipid droplet accumulation in macrophages. Proc Natl Acad Sci USA 101(3) 737-742 (2004).

Chang, C.C.Y., Huh, H.Y., Cadigan, K.M., et al. Molecular cloning and functional expression of human acyl-coenzyme A: Cholesterol acyltransferase cDNA in mutant chinese hamster ovary cells. J Biol Chem 268(28) 20747-20755 (1993).

Chang, C.C.Y., Chen, J., Thomas, M.A., et al. Regulation and immunolocalization of acyl-coenzyme A: Cholesterol acytransferase in mammalian cells as studies with specific antibodies. J Biol Chem 270(49) 29532-29540 (1995).

Chang, C.C.Y., Lee, C.G., Chang, E.T., et al. Recombinant acyl-CoA: cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner. J Biol Chem 273(52) 35132-35141 (1998).

Lee, R.G., Willingham, M.C., Davis, M.A., et al. Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. J Lipid Res 41 1991-2001 (2000).

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Size Price Quantity Subtotal
200 µg $107.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-10. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

ACAT-1 Polyclonal Antibody
ACAT-2 Polyclonal Antibody
Atherosclerosis Product Pack

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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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