ACAT-2 Blocking Peptide

Cayman Chemical Item Number 10005091

Sterol O-Acyltransferase 2; Cholesterol Acyltransferase 2; Acyl-coenzyme A: Cholesterol Acyltransferase-2

Description

Peptide sequence: human ACAT-2 amino acids 3-20 · To be used in conjunction with Cayman’s ACAT-2 polyclonal antibody (Catalog No. 100027) to block protein-antibody complex formation during immunochemical analysis for ACAT-2.

Synonyms

Sterol O-Acyltransferase 2
Cholesterol Acyltransferase 2
Acyl-coenzyme A: Cholesterol Acyltransferase-2

Formulation

200 µg of peptide in 200 µl TBS, pH 7.4, containing 0.1% BSA and 0.02% sodium azide

Stability

2 years

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Background Reading

Lee, R.G., Willingham, M.C., Davis, M.A., et al. Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. J Lipid Res 41 1991-2001 (2000).

Katsuren, K., Tamura, T., Arashiro, R., et al. Structure of the human acyl-CoA: Cholesterol acyltransferase-2 (ACAT-2) gene and its relation to dyslipidemia. Biochim Biophys Acta 1531 230-240 (2001).

Anderson, R.A., Joyce, C., Davis, M., et al. Identification of a form of acyl-CoA: Cholesterol acyltransferase specific to liver and intestine in nonhuman primates. J Biol Chem 273(41) 26747-26754 (1998).

Rudel, L.L., Lee, R.G., and Cockman, T.L. Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr Opin Lipidol 12 121-127 (2001).

Cases, S., Novak, S., Zheng, Y., et al. ACAT-2, a second mammalian acyl-CoA: Cholesterol acyltransferase. Its cloning, expression, and characterization. J Biol Chem 273(4) 26755-26764 (1998).

Oelkers, P., Behari, A., Cromley, D., et al. Characterization of two human genes encoding acyl coenzyme A: Cholesterol acyltransferase-related enzymes. J Biol Chem 273(41) 26765-26771 (1998).

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Subtotal

200 µg

$107.00

$0.00

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