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Daidzein

Cayman Chemical Item Number 10005166

Isoflavone (CAS 486-66-8)

Daidzein (CAS 486-66-8)

See more	Antioxidants (63) Flavonoids (20) Endocrinology (337) Nutrition/Diet (69) Oxidative Injury (291)

Description

Daidzein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, clover, kudzu, and other legumes. The estimated human normal dietary intake of daidzein, primarily as glycosides, is 0 to 0.3 mg/kg. Daidzein is present in much greater amounts in nutritional supplements. Daidzein is inactive as a tyrosine-specific inhibitor of protein kinase activity, and can be used as a negative control for genistein.¹ In adult animals, dietary genistein has numerous effects based on estrogen agonist/antagonist and antioxidant activities.²

1 Akiyama, T., Ishida, J., Nakagawa, S., et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262(1) 5592-5595 (1987).

2 Lamartiniere, C.A., Cotroneo, M.S., Fritz, W.A., et al. Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate. J Nutr 132 552S-558S (2002).

Synonyms	Isoflavone
Formal Name	7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number	486-66-8
Molecular Formula	C₁₅H₁₀O₄
Formula Weight	254.2
Formulation	A crystalline solid
Purity	≥98%
λ_max	249, 301 nm
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard Oc1ccc(cc1)c1coc2cc(O)ccc2c1=O

Background Reading

Akiyama, T., Ishida, J., Nakagawa, S., et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262(1) 5592-5595 (1987).

Lamartiniere, C.A., Cotroneo, M.S., Fritz, W.A., et al. Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate. J Nutr 132 552S-558S (2002).

Daidzein is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
100 mg	$10.00		$0.00
500 mg	$45.00		$0.00
1 g	$80.00		$0.00
5 g	$350.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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