See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Quercetin

Cayman Chemical Item Number 10005169

(CAS 117-39-5)

Quercetin (CAS 117-39-5)

See more

Description

Quercetin is a flavonoid compound found in the bark and rinds of many plants and fruits.1 The estimated human normal dietary intake of quercetin, primarily as glycosides, is 0.1-0.2 mg/kg.2 Quercetin is present in much greater amounts in nutritional supplements. Quercetin is carcinogenic in male rats, inducing renal adenomas when fed at 2,000 mg/kg.3 Quercetin has been reported to inhibit phosphodiesterases of both cGMP and cAMP.4,5

1 Gschwendt, M., Horn, F., Kittstein, W., et al. Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin.. Biochem Biophys Res Commun 117(2) 444-447 (1983).

2 Young, J.F., Nielsen, S.E., Haraldsdottir, J., et al. Effect of fruit juice intake on urinary quercetin excretion and biomarkers of antioxidative status.. Am J Clin Nutr 69(1) 87-94 (1999).

3 . Toxicology and carcinogenesis studies of quercetin in F344 rats. National Toxicology Program 1-171 (1992 Sep 1).

4 Ruckstuhl, M., Beretz, A., and Anton, R. Flavonoids are selective cyclic GMP phosphodiesterase inhibitors.. Biochem Pharmacol 28(4) 535-538 (1979).

5 Lang, D.R., and Racker, E. Effect of quercetin and F1 inhibitor on mitochondrial ATPase and energy-linked reactions in submitochondrial particles.. Biochim Biophys Acta 333(2) 180-186 (1974).

Formal Name 2-​(3,​4-​dihydroxyphenyl)-​3,​5,​7-​trihydroxy-​4H-​1-​benzopyran-​4-​one
CAS Number 117-39-5
Molecular Formula C15H10O7
Formula Weight 302.2
Formulation A crystalline solid
Purity >95%
λmax 256, 368 nm
Stability 2 years
Storage Room temperature
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
Oc1cc(O)​c2c(c1)​oc(c1ccc(O)​c(O)​c1)​c(O)​c2=O

Background Reading

Young, J.F., Nielsen, S.E., Haraldsdottir, J., et al. Effect of fruit juice intake on urinary quercetin excretion and biomarkers of antioxidative status.. Am J Clin Nutr 69(1) 87-94 (1999).

Ruckstuhl, M., Beretz, A., and Anton, R. Flavonoids are selective cyclic GMP phosphodiesterase inhibitors.. Biochem Pharmacol 28(4) 535-538 (1979).

Gschwendt, M., Horn, F., Kittstein, W., et al. Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin.. Biochem Biophys Res Commun 117(2) 444-447 (1983).

. Toxicology and carcinogenesis studies of quercetin in F344 rats. National Toxicology Program 1-171 (1992 Sep 1).

Lang, D.R., and Racker, E. Effect of quercetin and F1 inhibitor on mitochondrial ATPase and energy-linked reactions in submitochondrial particles.. Biochim Biophys Acta 333(2) 180-186 (1974).

Show all 5 Hide all but first 3

Quercetin is available in the following screening library:

Size Price Quantity Subtotal
5 g $12.00 $0.00
10 g $23.00 $0.00
50 g $96.00 $0.00
100 g $168.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-10. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Daidzein
Genistein
Hesperetin
Salidroside
Silybin
Zaprinast
Show all 6 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?