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Matairesinol

Cayman Chemical Item Number 10005174

(CAS 580-72-3)

Matairesinol (CAS 580-72-3)

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Description

Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets.1 Matairesinol is one of the principle lignans present in dietary fiber. It is absorbed directly, in addition to being further metabolized by enteric bacteria to enterolactone and enterodiol. Recent observations have shown an inverse association between serum enterolactone levels and serum isoprostane levels.2 This association implies a protective effect against oxidative injury associated with the dietary lignans themselves, enterolactone, or some intermediate in this pathway. There are also published reports of an inverse relationship between dietary lignans such as matairesinol and breast cancer incidence.3

1 Morton, L.W., Caccetta, R.A., Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease. Clin Exp Pharmacol Physiol 27 152-159 (2000).

2 Vanharanta, M., Voutilainen, S., Nurmi, T., et al. Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. Atherosclerosis 160 465-469 (2002).

3 Ingram, D., Sanders, K., Kolybaba, M., et al. Case-control study of phyto-oestrogens and breast cancer. Lancet 350 990-994 (1997).

Formal Name dihydro-​3R,​4R-​bis[(4-​hydroxy-​3-​methoxyphenyl)methyl]-​2(3H)-​furanone
CAS Number 580-72-3
Molecular Formula C20H22O6
Formula Weight 358.4
Formulation A crystalline solid
Purity ≥95%
λmax 230, 282 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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OC1=C(OC)​C=C(C[C@@H]​2[C@@H]​(CC3=CC(OC)​=C(O)​C=C3)​COC2=O)​C=C1

Background Reading

Morton, L.W., Caccetta, R.A., Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease. Clin Exp Pharmacol Physiol 27 152-159 (2000).

Ingram, D., Sanders, K., Kolybaba, M., et al. Case-control study of phyto-oestrogens and breast cancer. Lancet 350 990-994 (1997).

Vanharanta, M., Voutilainen, S., Nurmi, T., et al. Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. Atherosclerosis 160 465-469 (2002).

Matairesinol is available in the following screening library:

Size Price Quantity Subtotal
1 mg $30.00 $0.00
5 mg $120.00 $0.00
10 mg $180.00 $0.00
25 mg $338.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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