Cayman Chemical | Athero-PAK

10005292 Athero-PAK

• See more Immunohistochemistry; Western Blot; Antibodies; Lipids; Oxylipins; Phospholipids; PPAR; Atherosclerosis; Oxidative Injury

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

The Athero-PAK contains our human ACAT-1 polyclonal antibody and blocking peptide. Targeting human amino acids 6-23 of the acyl-Coenzyme A: cholesterol acyl transferase-1, these reagents can be used for western blot analysis and immunohistochemistry. Also included are several oxidized bioactive lipid species, including cholesteryl linoleate hydroperoxides,^1,2 POV-PC,³ and PGPC.⁴

1 Brooks, C.J.W., Harland, W.A., Steel, G., et al. Lipids of human atheroma: Isolation of hydroxyoctadecadienoic acids from advanced aortal lesions. Biochim Biophys Acta 202 563-566 (1970).

2 Lenz, M.L., Hughes, H., Mitchell, J.R., et al. Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein. J Lipid Res 31 1043-1050 (1990).

3 Podrez, E.A., Batyreva, B., Shen, Z., et al. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem 277(41) 38503-38516 (2002).

4 Leitinger, N., Tyner, T.R., Oslund, L., et al. Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils. Proc Natl Acad Sci USA 96(21) 12010-12015 (1999).

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Purchase 10005292 Athero-PAK

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-19.
Prices are subject to change without notice.