See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!
My Account 
❘ Contact 
❘ Cart 
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
Oleoyl Ethyl Amide ExclusiveCayman Chemical Item Number 10005459
N- 
Oleoyl Ethyl Amide (CAS 85075-82-7)
Description
Numerous analogs of fatty acyl ethanolamides potentiate the intrinsic biological activity of arachidonoyl ethanolamide (anandamide; AEA).1 This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty amide acyl hydrolase (FAAH) within the neurons.2 Oleoyl ethyl amide (OEtA) has potent FAAH inhibitory activity (IC50 5.25 nM in rat brain homogenates) but does not inhibit acidic PEAase or bind to CB1 or CB2 receptors. OEtA is therefore a selective FAAH inhibitor with potential analgesic and anxiolytic activity.3
1
Khanolkar, A.D., and Makriyannis, A. Structure-
2
Deutsch, D.G., Glaser, S.T., Howell, J.M., et al. The cellular uptake of anandamide is coupled to its breakdown by fatty-
3
Vandevoorde, S., Lavand'homme, P., Fowler, C.J., et al. Oleoylethylamide, an analgesic FAAH inhibitor which modulates endogenous anandamide, oleoylethanolamide, and 2-
Background ReadingDeutsch, D.G., Glaser, S.T., Howell, J.M., et al. The cellular uptake of anandamide is coupled to its breakdown by fatty- Vandevoorde, S., Lavand'homme, P., Fowler, C.J., et al. Oleoylethylamide, an analgesic FAAH inhibitor which modulates endogenous anandamide, oleoylethanolamide, and 2- Khanolkar, A.D., and Makriyannis, A. Structure- Oleoyl Ethyl Amide is available in the following screening library: |
This product is available in custom sizes and/or larger quantities. Please contact our Sales Department for a quote or to purchase. Pricing updated 2012-05-25. Prices are subject to change without notice. To ask for assistance with one of our products please contact a Technical Support Scientist. Warning This product is not for human or veterinary use. Related Products
Downloads
Batch-specific InformationLogin to access batch-specific information |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
Quick Search