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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

IP Receptor (human) Blocking Peptide

Cayman Chemical Item Number 10005519

Prostaglandin I2 Receptor; Prostacyclin Receptor; PGI2 Receptor

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Description

Peptide sequence: human IP receptor amino acids · To be used in conjunction with Cayman’s IP receptor (human) polyclonal antibody (Catalog No. 10005518) to block protein-antibody complex formation during immunochemical analysis for the IP receptor.
Synonyms
  • Prostaglandin I2 Receptor
  • Prostacyclin Receptor
  • PGI2 Receptor
Formulation Lyophilized peptide
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Aristoff, P.A., Johnson, P.D., and Harrison, A.W. Synthesis of 9-substituted carbacyclin analogues. J Org Chem 48 5341-5348 (1983).

Nakagawa, O., Tanaka, I., Usui, T., et al. Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system. Circulation 90 1643-1647 (1994).

Namba, T., Oida, H., Sugimoto, Y., et al. cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla. J Biol Chem 269 9986-9992 (1994).

Smyth, E.M., Nestor, P.V., and Fitzgerald, G.A. Agonist-dependent phosphorylation of an epitope-tagged human prostacyclin receptor. J Biol Chem 271(52) 33698-33704 (1996).

McLaughlin, V.V., Genthner, D.E., Panella, M.M., et al. Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension. N Engl J Med 338 273-277 (1998).

Southall, M.D., and Vasko, M.R. Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons. J Biol Chem 276(19) 16083-16091 (2001).

Murata, T., Ushikubi, F., Matsuoka, T., et al. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature 388 678-682 (1997).

Cui, Y., Kataoka, Y., Satoh, T., et al. Protective effect of prostaglandin I2 analogs on ischemic delayed neuronal damage in gerbils. Biochem Biophys Res Commun 265 301-304 (1999).

Cheng, Y., Austin, S.C., Rocca, B., et al. Role of prostacyclin in the cardiovascular response to thromboxane A2. Science 296 539-541 (2002).

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Size Price Quantity Subtotal
200 µg $107.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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