Cayman Chemical | N-Arachidonoyl Taurine

10005537 N-Arachidonoyl Taurine

Click image to enlarge

• See below for pricing and ordering

• See analysis tools

• See more Fatty Acids; Neuroscience

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl-L-serine (ARA-S), have been isolated and characterized from bovine brain.¹ During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, was discovered.² This novel class or compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.³ N-arachidonoyl taurine, a prominent N-acyl taurine, activates both TRPV1 and TRPV4 with EC₅₀ values of 28 and 21 µM, respectively.³

1 Huang, S.M., Bisogno, T., Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem 276(46) 42639-42644 (2001).

2 Cravatt, B.F., Maxey, K.M. . (2004).

3 Saghatelian, A., McKinney, M.K., Bandell, M., et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45(30) 9007-9015 (2006).

	Download Product Insert 114 Kb PDF
	Download Material Safety Data Sheet (MSDS) 19 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm

Purchase 10005537 N-Arachidonoyl Taurine

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Pricing updated 2010-03-18.
Prices are subject to change without notice.

Related Products

Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.