Cayman Chemical | N-Oleoyl Taurine | Description (CAS 52514-04-2)

10005609 N-Oleoyl Taurine

(CAS 52514-04-2)

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Several different arachidonoyl amino acids, including N-arachidonoyl dopamine and N-arachidonoyl serine, have been isolated and characterized from bovine brain.¹ During mass spectral lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, were discovered.² This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.³ N-Oleoyl taurine is an amino-acyl endocannabinoid isolated from rat brain that may activate TRPV1 and TRPV4.³

1 Huang, S.M., Bisogno, T., Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem 276(46) 42639-42644 (2001).

2 Cravatt, B.F., Maxey, K.M. . (2004).

3 Saghatelian, A., McKinney, M.K., Bandell, M., et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45(30) 9007-9015 (2006).

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Pricing updated 2010-03-18.
Prices are subject to change without notice.

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