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N-Oleoyl Taurine Exclusive

Cayman Chemical Item Number 10005609

(CAS 52514-04-2)

N-Oleoyl Taurine (CAS 52514-04-2)

See more	Cannabinoids (296) Endocannabinoids (54) Neuroscience (654)

Description

Several different arachidonoyl amino acids, including N-arachidonoyl dopamine and N-arachidonoyl serine, have been isolated and characterized from bovine brain.¹ During mass spectral lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, were discovered.² This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.³ N-Oleoyl taurine is an amino-acyl endocannabinoid isolated from rat brain that may activate TRPV1 and TRPV4.³

1 Huang, S.M., Bisogno, T., Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem 276(46) 42639-42644 (2001).

2 Cravatt, B.F., and Maxey, K.M. . (2004).

3 Saghatelian, A., McKinney, M.K., Bandell, M., et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45(30) 9007-9015 (2006).

Formal Name	2-[(1-oxo-9Z-octadecenyl)amino]-ethanesulfonic acid
CAS Number	52514-04-2
Molecular Formula	C₂₀H₃₉NO₄S
Formula Weight	389.6
Formulation	A solution in DMSO
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCC/C=C\CCCCCCCC(N([H])CCS(O)(=O)=O)=O

Background Reading

Huang, S.M., Bisogno, T., Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem 276(46) 42639-42644 (2001).

Cravatt, B.F., and Maxey, K.M. . (2004).

Saghatelian, A., McKinney, M.K., Bandell, M., et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45(30) 9007-9015 (2006).

N-Oleoyl Taurine is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
500 µg	$34.00		$0.00
1 mg	$65.00		$0.00
5 mg	$272.00		$0.00
10 mg	$476.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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