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PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt)

Cayman Chemical Item Number 10005616

DPPI-3-P-d62; Phosphatidylinositol-3-phosphate C16-d62

PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt)

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Description

PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt) contains 62 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions. It is intended for use as an internal standard for the quantification of PtdIns-(3)-P1 (1,2-dipalmitoyl) (ammonium salt) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns featuring deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. It is intended for use as an internal standard for the quantification of PtdIns-(3)-P1 by GC- or LC-mass spectrometry. This synthetic standard compound contains the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound.

1 Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

2 Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

Synonyms
  • DPPI-3-P-d62
  • Phosphatidylinositol-3-phosphate C16-d62
Formal Name 1-​(1,​2-​dihexadecanoyl(2,​2’,​3,​3’,​4,​4’,​5,​5’,​6,​6’,​7,​7’,​8,​8’,​9,​9’,​10,​10’,​11,​11’,​12,​12’,​13,​13’,​14,​14’,​15,​15’,​16,​16,​16-​d31)phosphatidyl)inositol-​3-​phosphate,​ diammonium salt
Molecular Formula C41H10D62O16P2 · 2NH4
Formula Weight 981.4
Formulation A lyophilized powder
Purity ≥99% deuterated product
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCC(=O)​OC[C@H]​(COP(=O)​(O)​O[C@H]​1C(O)​[C@@H]​(O)​C(O)​C(OP(=O)​(O)​O)​[C@H]​1O)​OC(=O)​CCCCC(C)​CC(C)​CCCCCCCC

Background Reading

Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).
Size Price Quantity Subtotal
25 µg $97.00 $0.00
50 µg $184.00 $0.00
100 µg $349.00 $0.00
500 µg $1,552.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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FAQs

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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