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10005764 8-iso Prostaglandin F2α Ethanolamide
8-Isoprostane Ethanolamide; 8-epi PGF2α Ethanolamide; 8-iso PGF2α Ethanolamide; iPF2α-III Ethanolamide
8-iso Prostaglandin F2α Ethanolamide Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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It has been reported that anandamide (AEA) can be used directly by cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases to produce ethanolamide congeners of the classical PGs, including PGF2α.1 PGF2α ethanolamide has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of fatty acid amide hydrolase-deficient mice.2 However, the accumulation of AEA can also lead to isoprostane-type peroxidative decomposition. 8-iso PGF2α ethanolamide is a standard that allows one to distinguish these non-enzymatic decomposition products from “prostamides” that could be of enzymatic origin.
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1
Bachur, N.R., Masek, K., Melmon, K.L., et al. Fatty acid amides of ethanolamine in mammalian tissues. J Biol Chem 240 1019-1024 (1965).
2
Weber, A., Ni, J., Ling, K.J., et al. Formation of prostamides from anandamide in FAAH knockout mice analyzed HPLC with tandem mass spectrometry. J Lipid Res 45 757-763 (2004).
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Purchase 10005764 8-iso Prostaglandin F2α Ethanolamide
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-09.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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