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Renin (human recombinant)

Cayman Chemical Item Number 10006217

See more	Enzyme Activity (146) Enzymes (119) Proteins (180) Recombinant Proteins (171) Atherosclerosis (323) Endocrinology (335) Hypertension (90) Renal Disease (32)

Description

Renin is an aspartyl protease of approximately 40 kDa produced in the kidney by juxtaglomerular cells of the macula densa.¹ Renin converts angiotensinogen into angiotensin I, activating a major arm of renal sodium and volume auto-regulation. Native human renin is a glycoprotein derived from preprorenin by sequential cleavage of 20 and 46 amino acid residues from the N-terminus of the 406 amino acid precursor. The enzyme provided by Cayman Chemical is the active, 340 amino acid protease produced in HEK cells transfected with a human renin expression construct.

1 Imai, T., Miyazaki, H., Hirose, S., et al. Cloning and sequence analysis of cDNA for human renin precursor. Proc Natl Acad Sci USA 80 7405-7409 (1983).

Formulation	A solution in sodium acetate buffer
Purity	>99% by SDS-PAGE
Stability	6 months
Storage	-80°C
Shipping	Wet ice in continental US; may vary elsewhere

Background Reading

Imai, T., Miyazaki, H., Hirose, S., et al. Cloning and sequence analysis of cDNA for human renin precursor. Proc Natl Acad Sci USA 80 7405-7409 (1983).

Size	Price	Quantity	Subtotal
5 µg	$63.00		$0.00
10 µg	$120.00		$0.00
25 µg	$279.00		$0.00
50 µg	$504.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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Downloads

	Download Product Insert 75 Kb PDF
	Download Material Safety Data Sheet (MSDS) 17 Kb PDF
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	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

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