Cayman Chemical | Estradiol | Description • 17β-Oestradiol; 17β-Estradiol; β-Estradiol (CAS 50-28-2)

10006315 Estradiol

17β-Oestradiol; 17β-Estradiol; β-Estradiol (CAS 50-28-2)

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Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.^1,2 Plasma estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.^3,4

1 Vance, D.E. Cholesterol and related derivatives. 2^nd ed., 725-748 (1988).

2 Miller, W.L., Tyrrell, J.B. The adrenal cortex. 3^rd edition, 555-711 (1995).

3 Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3^rd ed., 973-1015 (1995).

4 Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin Chem 37 838-844 (1991).

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Pricing updated 2010-03-16.
Prices are subject to change without notice.

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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.