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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Estradiol

Cayman Chemical Item Number 10006315

17β-Oestradiol; 17β-Estradiol; β-Estradiol (CAS 50-28-2)

Estradiol (CAS 50-28-2)

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Description

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.1,2 Plasma estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.3,4

1 Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

2 Miller, W.L., and Tyrrell, J.B. The adrenal cortex. 3rd edition 555-711 (1995).

3 Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3rd ed. 973-1015 (1995).

4 Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin Chem 37 838-844 (1991).

Synonyms
  • 17β-Oestradiol
  • 17β-Estradiol
  • β-Estradiol
Formal Name estra-​1,​3,​5(10)-​triene-​3,​17β-​diol
CAS Number 50-28-2
Molecular Formula C18H24O2
Formula Weight 272.4
Formulation A crystalline solid
Purity ≥98%
λmax 203, 281 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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Oc1ccc2c(CCC3C2CC[C@]​2(C)​[C@@H]​(O)​CCC32)​c1

Background Reading

Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

Miller, W.L., and Tyrrell, J.B. The adrenal cortex. 3rd edition 555-711 (1995).

Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin Chem 37 838-844 (1991).

Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3rd ed. 973-1015 (1995).

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Size Price Quantity Subtotal
500 mg $9.00 $0.00
1 g $17.00 $0.00
5 g $72.00 $0.00
10 g $126.00 $0.00
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Cart Total $0.00

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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