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Quinestrol

Cayman Chemical Item Number 10006320

W 3566; Ethynyl Estradiol-3-cyclopentyl ether; Estrovis (CAS 152-43-2)

Quinestrol (CAS 152-43-2)

See more	Hormone (24) Steroids (37) Endocrinology (335)

Description

Quinestrol is a synthetic estrogen that is effective in hormone replacement therapy.^1,2 It is a 3-cyclopentyl ether of ethynyl estradiol. After gastrointestinal absorption, it is stored in adipose tissue, where it is slowly released and metabolized in the liver to its active form, ethynyl estradiol. Quinestrol has found limited use in suppressing lactation in postpartum women and, in combination with synthetic progestogens, as contraceptive therapy, although additional studies are needed for both applications.

1 Baumgardner, S.B., Condrea, H., Daane, T.A., et al. Replacement estrogen therapy for menopausal vasomotor flushes. Comparison of Quinestrol and conjugated estrogens.. Obstet Gynecol 51(4) 445-452 (1978).

2 Skouby, S.O. Criteria for the selection of an optimal estrogen replacement.. Gynecol Endocrinol 15 60-67 (2001).

Synonyms	W 3566 Ethynyl Estradiol-3-cyclopentyl ether Estrovis
Formal Name	3-(cyclopentyloxy)-19-norpregna-1,3,5(10)-trien-20-yn-17α-ol
CAS Number	152-43-2
Molecular Formula	C₂₅H₃₂O₂
Formula Weight	364.5
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard C[C@@]12C(CC[C@]2(C#C)O)C(C3CC1)CCC4=C3C=CC(OC5CCCC5)=C4

Background Reading

Baumgardner, S.B., Condrea, H., Daane, T.A., et al. Replacement estrogen therapy for menopausal vasomotor flushes. Comparison of Quinestrol and conjugated estrogens.. Obstet Gynecol 51(4) 445-452 (1978).

Skouby, S.O. Criteria for the selection of an optimal estrogen replacement.. Gynecol Endocrinol 15 60-67 (2001).

Size	Price	Quantity	Subtotal
100 mg	$28.00		$0.00
250 mg	$67.00		$0.00
500 mg	$126.00		$0.00
1 g	$224.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

Diethylstilbestrol

Ethynyl Estradiol

Gestrinone

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