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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
FTY720 (S)-
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Description
1 Brinkmann, V., Pinschewer, D.D., Feng, L., et al. FTY720: Altered lymphocyte traffic results in allograft protection. Transplantation 72 764-769 (2001).
2
Brinkmann, V., Davis, M.D., Heise, C.E., et al. The immune modulator FTY720 targets sphingosine 1-
3 Albert, R., Hinterding, K., Brinkmann, V., et al. Novel immunomodulator FTY720 is phosphorylated in rats and humans to form a single stereoisomer. Identification, chemical proof, and biological characterization of the biologically active species and its enantiomer. J Med Chem 48 5373-5377 (2005).
4
Kiuchi, M., Adachi, K., Tomatsu, A., et al. Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-
5 Brinkmann, V. FTY720: Mechanism of action and potential benefit in organ transplantation. Yonsei Med J 45(6) 991-997 (2004).
6
Honig, S.M., Fu, S., Mao, X., et al. FTY720 stimulates multidrug transporter-
7
Payne, S.G., Oskeritizian, C.A., Griffiths, R., et al. The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-
| Synonyms |
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|---|---|
| Formal Name | (2S)-amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol |
| CAS Number | 402616-26-6 |
| Molecular Formula | C19H34NO5P |
| Formula Weight | 387.5 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| Stability | 2 years |
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| SMILES |
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Background Reading
Brinkmann, V. FTY720: Mechanism of action and potential benefit in organ transplantation. Yonsei Med J 45(6) 991-997 (2004).
Brinkmann, V., Pinschewer, D.D., Feng, L., et al. FTY720: Altered lymphocyte traffic results in allograft protection. Transplantation 72 764-769 (2001).
| Size | Price | Quantity | Subtotal |
|---|---|---|---|
| 500 µg | $56.00 | $0.00 | |
| 1 mg | $106.00 | $0.00 | |
| 5 mg | $448.00 | $0.00 | |
| 10 mg | $784.00 | $0.00 | |
| Bulk | Contact | ||
| Cart Total | $0.00 |
This product is available in custom sizes and/or larger quantities.
Please contact our Sales Department for a quote or to purchase.
Pricing updated 2012-05-25. Prices are subject to change without notice.
To ask for assistance with one of our products please contact a Technical Support Scientist.
Warning This product is not for human or veterinary use.
Related Products
| FTY720 |
| FTY720 Phosphate |
|
FTY720 (R)- |
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Sphingosine- |
Downloads
 | Download Product Insert 119 Kb PDF |
| Download Material Safety Data Sheet (MSDS) 19 Kb PDF |
|
Printer-friendly version of this page small PDF (usually less than 100 Kb) |
| • US Letter paper 8½″ × 11″ | |
| • A4 paper 21cm × 29.7cm | |
| Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details. |
Batch-specific Information
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.
Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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