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10006427 Berberine
Umbellatine; BBR
(CAS 633-65-8)
Berberine Workbook Links
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Berberine is a widely distributed berberidaceaen alkaloid that has been employed in traditional medicine as an antiprotozoal and antidiarrheal agent. Berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides in both humans (at 1 g/day) and hamsters fed 50 mg/kg/day along with a high fat diet.1 Berberine does not act through 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibition, but instead enhances LDL-receptor protein and mRNA levels in hepatocytes. Berberine is therefore a natural product that may help control serum cholesterol without the side effects typical of the statin family of hypocholesterolemic drugs.
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1
Kong, W., Wei, J., Abidi, P., et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nature Med 10(12) 1344-1351 (2004).
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-17.
Prices are subject to change without notice.
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