Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Estrone

Cayman Chemical Item Number 10006485

E₁ (CAS 53-16-7)

Estrone (CAS 53-16-7)

See more	Hormone (24) Steroids (37) Endocrinology (335)

Description

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol.¹ Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.^1,2 Serum concentrations of estrone in premenopausal women fluctuate according to the menstral cycle and becomes the most predominant estrogen in postmenopausal women.¹ The binding affinities of estrone to the estrogen receptors α and β (ERα and ERβ) are approximately 60% and 37% relative to estradiol.¹

1 Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).

2 Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

Synonyms	E1
Formal Name	3-hydroxy-estra-1,3,5(10)-trien-17-one
CAS Number	53-16-7
Molecular Formula	C₁₈H₂₂O₂
Formula Weight	270.4
Formulation	A crystalline solid
Purity	≥95%
λ_max	281 nm
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard Oc1ccc2c(CC[C@@H]3C2CC[C@]2(C)C(=O)CCC32)c1

Background Reading

Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).

Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

Size	Price	Quantity	Subtotal
500 mg	$8.00		$0.00
1 g	$15.00		$0.00
5 g	$64.00		$0.00
10 g	$112.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

2,3-bis (4-Hydroxyphenyl) Propionitrile

Estrogen Receptor Polyclonal Antibody

Show all 13 Hide all but first 3

Downloads

	Download Product Insert 126 Kb PDF
	Download Material Safety Data Sheet (MSDS) 17 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640