10006486  Ethynyl Estradiol

(CAS 57-63-6)

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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.1 Ethynyl estradiol is a synthetic analog of estradiol used commonly as an oral contraceptive, often in combination with a progestin such as norgestrel/levonorgestrel or desogestrel. Efficacy of oral administration of ethynyl estradiol is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Ethynyl estradiol is also rapidly and almost completely absorbed from the gastrointestinal tract.2
1  Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).
2  Coelingh Bennink, H.J.T. Are all estrogens the same?. Maturitas 47 269-275 (2003).


Purchase 10006486 Ethynyl Estradiol

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-16.
Prices are subject to change without notice.

Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.

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