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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Ethynyl Estradiol

Cayman Chemical Item Number 10006486

(CAS 57-63-6)

Ethynyl Estradiol (CAS 57-63-6)

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Description

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.1 Ethynyl estradiol is a synthetic analog of estradiol used commonly as an oral contraceptive, often in combination with a progestin such as norgestrel/levonorgestrel or desogestrel. Efficacy of oral administration of ethynyl estradiol is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Ethynyl estradiol is also rapidly and almost completely absorbed from the gastrointestinal tract.2

1 Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).

2 Coelingh Bennink, H.J.T. Are all estrogens the same? Maturitas 47 269-275 (2003).

Formal Name 19-​norpregna-​1,​3,​5(10)-​trien-​20-​yne-​3,​17α-​diol
CAS Number 57-63-6
Molecular Formula C20H24O2
Formula Weight 296.4
Formulation A crystalline solid
Purity ≥98%
λmax 281 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCC1(O)​CCC2[C@@H]​3CCc4cc(O)​ccc4C3CC[C@]​12C

Background Reading

Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens. N Engl J Med 346(5) 340-352 (2002).

Coelingh Bennink, H.J.T. Are all estrogens the same? Maturitas 47 269-275 (2003).

Size Price Quantity Subtotal
100 mg $8.00 $0.00
500 mg $18.00 $0.00
1 g $48.00 $0.00
5 g $160.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-02-10. Prices are subject to change without notice.

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