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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Dihomo-γ-Linolenic Acid methyl ester

Cayman Chemical Item Number 10006580

Methyl DGLA (CAS 21061-10-9)

Dihomo-γ-Linolenic Acid methyl ester (CAS 21061-10-9)

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Description

Dihomo-γ-linolenic acid (DGLA) is a metabolite produced by chain elongation of the essential fatty acid γ-linolenic acid. Methyl DGLA is an esterified version of the free acid which is less water soluble, but more ammenable for the formulation of DGLA-containing diets and dietary supplements. DGLA has been advanced as a possible treatment for various inflammatory disorders.1,2 Evening primrose oil is a DGLA-rich nutraceutical which has been advocated for such uses.

1 Schalin-Karrila, M., Mattila, L., Jansen, C.T., et al. Evening primrose oil in the treatment of atopic eczema: Effect on clinical status, plasma phospholipid fatty acids, and circulating blood prostaglandins. Br J Dermatol 117 11-19 (1987).

2 Yagaloff, K.A., Franco, L., Simko, B., et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids 52 293-297 (1995).

Synonyms
  • Methyl DGLA
Formal Name 8Z,​11Z,​14Z-​eicosatrienoic acid,​ methyl ester
CAS Number 21061-10-9
Molecular Formula C21H36O2
Formula Weight 320.5
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(OC)​=O

Background Reading

Schalin-Karrila, M., Mattila, L., Jansen, C.T., et al. Evening primrose oil in the treatment of atopic eczema: Effect on clinical status, plasma phospholipid fatty acids, and circulating blood prostaglandins. Br J Dermatol 117 11-19 (1987).

Yagaloff, K.A., Franco, L., Simko, B., et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids 52 293-297 (1995).

Dihomo-γ-Linolenic Acid methyl ester is available in the following screening libraries:

Size Price Quantity Subtotal
10 mg $20.00 $0.00
50 mg $90.00 $0.00
100 mg $160.00 $0.00
500 mg $700.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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