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Docosahexaenoic Acid methyl ester

Cayman Chemical Item Number 10006865

Cervonic Acid methyl ester; DHA methyl ester (CAS 2566-90-7)

Docosahexaenoic Acid methyl ester (CAS 2566-90-7)

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Description

Docosahexaenoic acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.1 Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.2 Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.3 DHA methyl ester is an ester version of the free acid which is less water soluble, but more amenable for the formulation of fatty acid-containing diets and dietary supplements.4

1 Salem, N., Kim, H., and Yergey, J.A. Docosahexaenoic acid: Membrane function and metabolism. 263-317 (1986).

2 Hoffman, D.R., Uauy, R., and Birch, D.G. Metabolism of ω-3 fatty acids in patients with autosomal dominant retinitis pigmentosa. Exp Eye Res 60 279-289 (1995).

3 Weisinger, H.S., Armitage, J.A., Sinclair, A.J., et al. Perinatal ω-3 fatty acid deficiency affects blood pressure later in life. Nat Med 7(3) 258-259 (2001).

4 Yagaloff, K.A., Franco, L., Simko, B., et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids 52 293-297 (1995).

Synonyms
  • Cervonic Acid methyl ester
  • DHA methyl ester
Formal Name 4Z,​7Z,​10Z,​13Z,​16Z,​19Z-​docosahexaenoic acid,​ methyl ester
CAS Number 2566-90-7
Molecular Formula C23H34O2
Formula Weight 342.5
Formulation A solution in ethanol
Purity ≥98%
Stability 6 months
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)​OC

Background Reading

Salem, N., Kim, H., and Yergey, J.A. Docosahexaenoic acid: Membrane function and metabolism. 263-317 (1986).

Yagaloff, K.A., Franco, L., Simko, B., et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids 52 293-297 (1995).

Weisinger, H.S., Armitage, J.A., Sinclair, A.J., et al. Perinatal ω-3 fatty acid deficiency affects blood pressure later in life. Nat Med 7(3) 258-259 (2001).

Hoffman, D.R., Uauy, R., and Birch, D.G. Metabolism of ω-3 fatty acids in patients with autosomal dominant retinitis pigmentosa. Exp Eye Res 60 279-289 (1995).

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Docosahexaenoic Acid methyl ester is available in the following screening library:

Size Price Quantity Subtotal
50 mg $19.00 $0.00
100 mg $36.00 $0.00
500 mg $152.00 $0.00
1 g $266.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

4,5-dehydro Docosahexaenoic Acid
Docosahexaenoic Acid
Docosahexaenoic Acid-d5

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