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10006908 Adipogenesis Assay Kit
Adipogenesis Assay Kit Workbook Links
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Obesity is a growing concern worldwide and has reached epidemic proportions in the United States.1 It is a risk factor in many major chronic diseases that afflict our society, including cardiovascular disease, diabetes mellitus, and cancer. In recent years, numerous studies have focused on identifying the mechanism of development of obesity, which is a process of either increasing the number of fat cells (fat cell hyperplasia) or enlargement of fat cells with each cell carrying greater amounts of fat (fat cell hypertrophy), or both.2,1 The ability to regulate the cell cycle and differentiation of adipocytes are key in the development and physiology of obesity and also in the origin of cancer. Understanding of these processes is critical to a rational approach to the treatment of obesity and cancer. Cayman’s Adipogenesis Assay Kit provides the reagents required for studying the induction and inhibition of adipogenesis in the established 3T3-L1 model, using the adipogenesis induction procedure. This kit can also be used to screen drug candidates involved in adipogenesis. The classic Oil Red O staining for lipid droplets is used in this kit as an indicator of the degree of adipogenesis, and can be quantified with a plate reader after the dye is conveniently extracted from the lipid droplet.
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1
Camp, H.S., Ren, D., Leff, T. Adipogenesis and fat-cell function in obesity and diabetes. Trends in Molecular Medicine 8(9) 442-447 (2002).
2
Spiegelman, B.M., Flier, J.S. Adipogenesis and obesity: Rounding out the big picture. Cell 87 377-389 (1995).
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Purchase 10006908 Adipogenesis Assay Kit
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
Please contact our
Sales Department
for a quote or to purchase.
Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services.
To ask for assistance with one of our products please contact our Technical Help staff.
Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-19.
Prices are subject to change without notice.
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