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15(S)-HETE Lipid Maps MS Standard

Cayman Chemical Item Number 10007251

(CAS 54845-95-3)

15(S)-HETE Lipid Maps MS Standard (CAS 54845-95-3)

See more	Mass Spectrometry (253) Inhibitors (493) Leukotrienes (90) Lipoxygenase (84) Oxylipins (226) Allergy/Asthma (97) Apoptosis (183) Cancer (606)

Description

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.¹ 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.²

1 Nadel, J.A., Conrad, D.J., Ueki, I.F., et al. Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cells. J Clin Invest 87 1139-1145 (1991).

2 Ramis, I., Roselló-Catafau, J., Bulbena, O., et al. 15-Hydroxyeicosatetraenoic acid as a major eicosanoid in nasal secretions: Assay by high-performance liquid chromatographic-radioimmunoassay and gas chromatographic-mass spectrometric procedures. J Chromatogr 496 416-422 (1989).

Formal Name	15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
CAS Number	54845-95-3
Molecular Formula	C₂₀H₃₂O₃
Formula Weight	320.5
Formulation	A solution in ethanol
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCC(O)\C=C\C=C\C/C=C\C/C=C\CCCC(=O)O

Background Reading

Ramis, I., Roselló-Catafau, J., Bulbena, O., et al. 15-Hydroxyeicosatetraenoic acid as a major eicosanoid in nasal secretions: Assay by high-performance liquid chromatographic-radioimmunoassay and gas chromatographic-mass spectrometric procedures. J Chromatogr 496 416-422 (1989).

Nadel, J.A., Conrad, D.J., Ueki, I.F., et al. Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cells. J Clin Invest 87 1139-1145 (1991).

Size	Price	Quantity	Subtotal
25 µg	$36.00		$0.00
50 µg	$68.00		$0.00
100 µg	$130.00		$0.00
500 µg	$576.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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