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5(6)-EET Lipid Maps MS Standard

Cayman Chemical Item Number 10007260

5(6)-EpETrE

5(6)-EET Lipid Maps MS Standard

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Description

5(6)-EET is biosynthesized in rat and rabbit liver microsomes by cCYP450.1,2 In neuroendocrine cells, such as the anterior pituitary and pancreatic islet, 5(6)-EET has been implicated in the mobilization of Ca2+ and hormone secretion.3,4

1 Chacos, N., Falck, J.R., Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochem Biophys Res Commun 104 916-922 (1982).

2 Oliw, E.H., Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. J Biol Chem 257 3771-3781 (1982).

3 Snyder, C., Lattanzio, F., Yadagiri, P., et al. 5,6-Epoxyeicosatrienoic acid mobilizes Ca2+ in anterior pituitary cells. Biochem Biophys Res Commun 139 1188-1194 (1986).

4 Falck, J.R., Manna, S., Moltz, J., et al. Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets. Biochem Biophys Res Commun 114 743-749 (1983).

Synonyms
  • 5(6)-EpETrE
Formal Name (±)5(6)-​epoxy-​8Z,​11Z,​14Z-​eicosatrienoic acid
Molecular Formula C20H32O3
Formula Weight 320.5
Formulation A solution in acetonitrile
Purity ≥98%
Stability 6 months
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\C/C=C\CC1OC1CCCC(=O)​O

Background Reading

Oliw, E.H., Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. J Biol Chem 257 3771-3781 (1982).

Chacos, N., Falck, J.R., Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochem Biophys Res Commun 104 916-922 (1982).

Falck, J.R., Manna, S., Moltz, J., et al. Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets. Biochem Biophys Res Commun 114 743-749 (1983).

Snyder, C., Lattanzio, F., Yadagiri, P., et al. 5,6-Epoxyeicosatrienoic acid mobilizes Ca2+ in anterior pituitary cells. Biochem Biophys Res Commun 139 1188-1194 (1986).

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Size Price Quantity Subtotal
25 µg $40.00 $0.00
50 µg $76.00 $0.00
100 µg $144.00 $0.00
500 µg $640.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

(±)5,6-DHET
(±)5,6-DHET lactone Exclusive
5(6)-EET
5(6)-EET methyl ester
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