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10007268 Arachidonic Acid Lipid Maps MS Standard
(CAS 506-32-1)
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Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1 Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.2
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1
Nixon, A.B., Greene, D.G., Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim Biophys Acta 1300 187-196 (1996).
2
Burgoyne, R.D., Morgan, A. The control of free arachidonic acid levels. Trends Biochem Sci 15 365-366 (1990).
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Pricing updated 2010-03-12.
Prices are subject to change without notice.
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