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Palmitic Acid methyl ester

Cayman Chemical Item Number 10007358

MP; Methyl Palmitate (CAS 112-39-0)

Palmitic Acid methyl ester (CAS 112-39-0)

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Description

Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake, and approximately 25% of the total plasma fatty acids in plasma lipoproteins.1 Saturated free fatty acids induce the expression of cyclooxygenase-2.2 Palmitic acid methyl ester (MP) is a fatty acid ester whose concentration in cells is modulated by methanol. In studies with isolated Kupffer cells, MP inhibits phagocytosis and decreases cell viability. In cells treated with lipopolysaccharide, it also decreases secretion of interleukin-10, TNF-α, nitric oxide, and prostaglandin E2. This effect is thought to occur by the inhibition of NF-κB.3

1 Santos, M.J., López-Jurado, M., Llopis, J., et al. Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Ann Nutr Metab 39 52-62 (1995).

2 Lee, J.Y., Sohn, K.H., Rhee, S.H., et al. Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through toll-like receptor 4. J Biol Chem 276(20) 16683-16689 (2001).

3 Cai, P., Kaphalia, B.S., and Ansari, G.A.S. Methyl palmitate: Inhibitor of phagocytosis in primary rat Kupffer cells. Toxicology 210 197-204 (2005).

Synonyms
  • MP
  • Methyl Palmitate
Formal Name hexadecanoic acid,​ methyl ester
CAS Number 112-39-0
Molecular Formula C17H34O2
Formula Weight 270.5
Formulation A crystalline solid
Purity >99%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCC(OC)​=O

Background Reading

Santos, M.J., López-Jurado, M., Llopis, J., et al. Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Ann Nutr Metab 39 52-62 (1995).

Cai, P., Kaphalia, B.S., and Ansari, G.A.S. Methyl palmitate: Inhibitor of phagocytosis in primary rat Kupffer cells. Toxicology 210 197-204 (2005).

Lee, J.Y., Sohn, K.H., Rhee, S.H., et al. Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through toll-like receptor 4. J Biol Chem 276(20) 16683-16689 (2001).

Palmitic Acid methyl ester is available in the following screening libraries:

Size Price Quantity Subtotal
1 g $9.00 $0.00
5 g $41.00 $0.00
10 g $72.00 $0.00
25 g $158.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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