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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Arachidonic Acid-biotin

Cayman Chemical Item Number 10007466

Arachidonic Acid-biotin

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Description

Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1 Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signalling and inflammation.2 Arachidonic acid-biotin was designed to allow arachidonic acid to be detected in complexes with protein binding partners such as fatty acid binding proteins (FABPs). It is thus a tool to be used in the general elucidation of the signaling and transport of free arachidonic acid.

1 Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim Biophys Acta 1300 187-196 (1996).

2 Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels. Trends Biochem Sci 15 365-366 (1990).

Formal Name 5Z,​8Z,​11Z,​14Z-​eicosatetraenoyl-​N'-​biotinoyl-​1,​5-​diaminopentane
Molecular Formula C35H58N4O3S
Formula Weight 614.9
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)​NCCCCCNC(=O)​CCCCC1SCC2NC(=O)​NC12

Background Reading

Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels. Trends Biochem Sci 15 365-366 (1990).

Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim Biophys Acta 1300 187-196 (1996).
Size Price Quantity Subtotal
100 µg $45.00 $0.00
500 µg $203.00 $0.00
1 mg $360.00 $0.00
5 mg $1,575.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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