Cayman Chemical | δ-CEHC

10007706 δ-CEHC

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• See more Antioxidants; Endocrinology; Nutrition/Diet; Oxidative Injury

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Molecules having vitamin E antioxidant activity include four tocopherols (α, β, γ, δ) and four tocotrienols (α, β, γ, δ).¹ One form, α-tocopherol has the highest biological activity based on fetal resorption assays.² δ-CEHC is a major β-oxidation metabolite of δ-tocopherol.^3,4 Approximately 50% of a 3H-δ-tocopherol given as an intraperitoneal dose in rat is recovered in the urine as δ-CEHC, indicating this is the major route of metabolism.⁴

1 Kamal-Eldin, A., Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).

2 Weiser, H., Riss, G., Kormann, A.F. Biodiscrimination of the eight α-tocopherol stereoisomers results in preferential accumulation of the four 2R forms in tissues and plasma of rats. J Nutr 126(10) 2539-2549 (1996).

3 Christen, S., Woodall, A.A., Shigenaga, M.K., et al. γ-Tocopherol traps mutagenic electrophiles such as NOx and complements a-tocopherol: Physiological implications. Proc Natl Acad Sci USA 94 3217-3222 (1997).

4 Chiku, S., Hamamura, K., Nakamura, T. Novel urinary metabolite of d-δ-tocopherol in rats. J Lipid Res 25 40-48 (1984).

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Pricing is for North America only. Other customers should contact a distributor in their region.

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-15.
Prices are subject to change without notice.

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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.