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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

13,14-dihydro-15-keto Prostaglandin F2α-d4

Cayman Chemical Item Number 10007793

PGFM-d4

13,14-dihydro-15-keto Prostaglandin F2α-d4

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Description

13,14-dihydro-15-keto Prostaglandin F2α-d4 (13,14-dihydro-15-keto PGF2α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGF2α by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGF2α is the first prominent plasma metabolite of PGF2α in the 15-hydroxy PGDH pathway.1 Measurement of 13,14-dihydro-15-keto PGF2α in plasma can be used as a marker of the in vivo production of PGF2α.1,2,3

1 Samuelsson, B., Goldyne, M., Granström, E., et al. Prostaglandins and thromboxanes. Annu Rev Biochem 47 997-1029 (1978).

2 Del Vecchio, R.P., Maxey, K.M., and Lewis, G.S. A quantitative solid-phase enzymeimmunoassay for 13,14-dihydro-15-keto-prostaglandin F2α in plasma. Prostaglandins 43 321-330 (1992).

3 Meyer, H.H.D., Eisele, K., and Osaso, J. A biotin-streptavidin amplified enzyme immunoassay for 13,14-dihydro-15-keto-PGF2α. Prostaglandins 38 375-383 (1989).

Synonyms
  • PGFM-d4
Formal Name 9α,​11α-​dihydroxy-​15-​oxo-​prost-​5Z-​en-​1-​oic-​3,​3,​4,​4-​d4 acid
Molecular Formula C20H30D4O5
Formula Weight 358.5
Formulation A solution in methyl acetate
Purity ≥99% deuterated product
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCC(=O)​CC[C@H]​1C(O)​CC(O)​C1C/C=C\CCCC(=O)​O

Background Reading

Samuelsson, B., Goldyne, M., Granström, E., et al. Prostaglandins and thromboxanes. Annu Rev Biochem 47 997-1029 (1978).

Meyer, H.H.D., Eisele, K., and Osaso, J. A biotin-streptavidin amplified enzyme immunoassay for 13,14-dihydro-15-keto-PGF2α. Prostaglandins 38 375-383 (1989).

Del Vecchio, R.P., Maxey, K.M., and Lewis, G.S. A quantitative solid-phase enzymeimmunoassay for 13,14-dihydro-15-keto-prostaglandin F2α in plasma. Prostaglandins 43 321-330 (1992).
Size Price Quantity Subtotal
50 µg $56.00 $0.00
100 µg $106.00 $0.00
500 µg $448.00 $0.00
5 mg $3,360.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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