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17-phenyl trinor 8-iso Prostaglandin E2

Cayman Chemical Item Number 10007931

17-phenyl trinor 8-iso Prostaglandin E2

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Description

17-phenyl trinor 8-iso Prostaglandin E2 (17-phenyl trinor 8-iso PGE2) is the C-8 epimer of 17-phenyl trinor PGE2, a synthetic analog of PGE2. 17-phenyl trinor PGE2 is an EP1 and EP3 receptor agonist that causes contraction of the guinea pig ileum at a concentration of 11 µM.1 There are no published studies of the pharmacological properties of 17-phenyl trinor 8-iso PGE2.

1 Lawrence, R.A., Jones, R.L., and Wilson, N.H. Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea-pig ileum. Br J Pharmacol 105 271-278 (1992).

Formal Name 9-​oxo-​11α,​15S-​dihydroxy-​17-​phenyl-​18,​19,​20-​trinor-​(8β)-​prosta-​5Z,​13E-​dien-​1-​oic acid
Molecular Formula C23H28O5
Formula Weight 384.5
Formulation A crystalline solid
Purity ≥95%
λmax 207 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O=C1C[C@@H]​(O)​[C@H]​(/C=C/[C@@H]​(O)​CCC2=CC=CC=C2)​[C@@H]​1C/C=C\CCCC(O)​=O

Background Reading

Lawrence, R.A., Jones, R.L., and Wilson, N.H. Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea-pig ileum. Br J Pharmacol 105 271-278 (1992).

17-phenyl trinor 8-iso Prostaglandin E2 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $134.00 $0.00
5 mg $603.00 $0.00
10 mg $1,072.00 $0.00
25 mg $2,345.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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