10007963  E-64

(CAS 66701-25-5)

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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Related Articles

Sarabia, F., Sánchez-Ruiz, A., Chammaa, S. Steroselective synthesis of E-64 and related cysteine proteases inhibitors from 2,3-epoxyamides. Bioorg Med Chem 13 1691-1705 (2005).

Barrett, A.J., Kembhavi, A.A., Brown, M.A., et al. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochem J 201 189-198 (1982).

Giusti, I., D'Ascenzo, S., Millimaggi, D., et al. Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles. Neoplasia 10(5) 481-488 (2008).

Drew, M.E., Banerjee, R., Uffman, E.W., et al. Plasmodium food vacuole plasmepsins are activated by falcipains. J Biol Chem 283(19) 12870-12876 (2008).

Drahl, C., Cravatt, B.F., Sorensen, E.J. Protein-reactive natural products. Natural Products Chemistry 44 5788-5809 (2005).

Susa, M., Luong-Nguyen, N., Cappellen, D., et al. Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical assay. Journal of Translational Medicine (2004).

Ahlberg, J., Berkenstam, A., Henell, F., et al. Degradation of short and long lived proteins in isolated rat liver lysosomes; effects of pH, temperature, and proteolytic inhibitors. J Biol Chem 260(9) 5847-5854 (1985).



Purchase 10007963 E-64

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Pricing updated 2010-03-17.
Prices are subject to change without notice.

Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.

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