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ent-Prostaglandin F2α

Cayman Chemical Item Number 10008122

(−)-Prostaglandin F2α; ent-PGF2α (CAS 54483-31-7)

ent-Prostaglandin F2α (CAS 54483-31-7)

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Description

Enzymatically-derived Prostaglandin F2α (PGF2α) is an optically pure compound whereas PGF2α derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGF2α is the opposite enantiomer of PGF2α. This compound can only be generated via the isoprostane pathway of free radical-catalyzed lipid peroxidation and has been implicated as a marker of oxidative stress. Levels of ent-PGF2α are elevated in human urine from heavy cigarette smokers and patients with hypercholesterolemia.1

1 Yin, H., Gao, L., Tai, H., et al. Urinary prostaglandin F2α is generated from the isoprostane pathway and not the cyclooxygenase in humans. J Biol Chem 282(1) 329-336 (2007).

Synonyms
  • (-)-Prostaglandin F2α
  • ent-PGF2α
Formal Name 9β,​11β,​15R-​trihydroxy-​(8β,​12α)-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 54483-31-7
Molecular Formula C20H34O5
Formula Weight 354.5
Formulation A solution in methyl acetate
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O[C@H]​1[C@@H]​(C/C=C\CCCC(O)​=O)​[C@H]​(/C=C/[C@H]​(O)​CCCCC)​[C@@H]​(O)​C1

Background Reading

Yin, H., Gao, L., Tai, H., et al. Urinary prostaglandin F2α is generated from the isoprostane pathway and not the cyclooxygenase in humans. J Biol Chem 282(1) 329-336 (2007).

ent-Prostaglandin F2α is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $52.00 $0.00
5 mg $234.00 $0.00
10 mg $416.00 $0.00
50 mg $1,820.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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