Linoleic acid is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet. Deficiencies in linoleic acid are linked to defective wound healing, growth retardation, and dermatitis.1,2 Linoleic acid is metabolized by 15-lipoxygenase in both plants and animals to form 9- and 13-HODE.3 Linoleic acid ethyl ester is a neutral, lipid-soluble form of linoleic acid.
1
Hashimoto, A., Katagiri, M., Torii, S., et al. Effect of the dietary α-linolenate/linoleate balance on leukotriene production and histamine release in rats. Prostaglandins363-15(1988).
2
Soyland, E., Fund, J., Rajka, G., et al. Effect of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis. N Engl J Med3281812-1816(1993).
3
Vick, B.A. Oxygenated fatty acids of the lipoxygenase pathway. 167-191(1993).
Synonyms
Ethyl Linoleate
Telfairic Acid ethyl ester
Formal Name
9Z,12Z-octadecadienoic acid, ethyl ester
CAS Number
544-35-4
Molecular Formula
C20H36O2
Formula Weight
308.5
Formulation
A solution in ethanol
Purity
>98%
Stability
1 year
Storage
-20°C
Shipping
Wet ice
in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\CCCCCCCC(OCC)=O
Background Reading
Hashimoto, A., Katagiri, M., Torii, S., et al. Effect of the dietary α-linolenate/linoleate balance on leukotriene production and histamine release in rats. Prostaglandins363-15(1988).
Vick, B.A. Oxygenated fatty acids of the lipoxygenase pathway. 167-191(1993).
Soyland, E., Fund, J., Rajka, G., et al. Effect of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis. N Engl J Med3281812-1816(1993).
Linoleic Acid ethyl ester is available in the following screening
libraries: