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Palmitoleic Acid ethyl ester

Cayman Chemical Item Number 10008204

Ethyl Palmitoleate (CAS 56219-10-4)

Palmitoleic Acid ethyl ester (CAS 56219-10-4)

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Description

Palmitoleic acid (9-hexadecenoic acid) is an unsaturated fatty acid that is found in highest concentration in the liver. It is a common component of the glycerides of human adipose tissues. Two other sources of palmitoleic acid are macadamia oil and sea buckthorn oil which contain about 20% and 40% of total fatty acid composition, respectively.1,2 Palmitoleic acid ethyl ester (ethyl palmitoleate) is a more lipophilic form of the free acid. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol. Ethyl palmitoleate (10-100 µM) in addition to 850 mM ethanol resulted in sustained, concentration-dependent increases in Ca2+ that caused cell death.3 This fatty acid ethyl ester is also a potential biomarker for fetal exposure to alcohol.4

1 Yang, B., and Kallio, H.P. Fatty acid composition of lipids in sea buckthorn (Hippophaë rhamnoids L.) berries of different origins. J Agric Food Chem 49 1939-1947 (2001).

2 Fard, A.M., Turner, A.G., and Willett, G.D. High-resolution electrospray-ionization fourier-transform ion cyclotron resonance and gas chromatography-mass spectrometry of macadamia nut oil. Aust J Chem 56 499-508 (2003).

3 Criddle, D.N., Raraty, M.G.T., Neoptolemos, J.P., et al. Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites. Proc Natl Acad Sci USA 101(29) 10738-10743 (2004).

4 Moore, C., Jones, J., Lewis, D., et al. Prevalence of fatty acid ethyl esters in meconium specimens. Clin Chem 49(1) 133-136 (2003).

Synonyms
  • Ethyl Palmitoleate
Formal Name 9Z-​hexadecenoic acid,​ ethyl ester
CAS Number 56219-10-4
Molecular Formula C18H34O2
Formula Weight 282.5
Formulation A solution in ethanol
Purity >95%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CCCCCC/C=C\CCCCCCCC(OCC)​=O

Background Reading

Yang, B., and Kallio, H.P. Fatty acid composition of lipids in sea buckthorn (Hippophaë rhamnoids L.) berries of different origins. J Agric Food Chem 49 1939-1947 (2001).

Fard, A.M., Turner, A.G., and Willett, G.D. High-resolution electrospray-ionization fourier-transform ion cyclotron resonance and gas chromatography-mass spectrometry of macadamia nut oil. Aust J Chem 56 499-508 (2003).

Criddle, D.N., Raraty, M.G.T., Neoptolemos, J.P., et al. Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites. Proc Natl Acad Sci USA 101(29) 10738-10743 (2004).

Moore, C., Jones, J., Lewis, D., et al. Prevalence of fatty acid ethyl esters in meconium specimens. Clin Chem 49(1) 133-136 (2003).

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Palmitoleic Acid ethyl ester is available in the following screening libraries:

Size Price Quantity Subtotal
10 mg $11.00 $0.00
50 mg $50.00 $0.00
100 mg $88.00 $0.00
500 mg $385.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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