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PtdIns-(3)-P₁ (1,2-dioctanoyl) (sodium salt)

Cayman Chemical Item Number 10008394

Phosphatidylinositol-3-monophosphate C-8 (sodium salt); DOPI-3-P₁ (sodium salt)

PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt)

See more	Inositol Phosphates (78) Phospholipids (58) Cell Cycle (71) Signal Transduction (314)

Description

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.^1,2 PtdIns-(3)-P₁ (1,2-dioctanoyl) is a synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and DAG stereochemistry as the natural compound. PtdIns-(3)-P₁ can be phosphorylated to di- (PtdIns-P₂; PIP₂) and triphosphates (PtdIns-P₃; PIP₃) by phosphatidyl inositol (PI)-specific kinases.

1 Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

2 Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

Synonyms	Phosphatidylinositol-3-monophosphate C-8 (sodium salt) DOPI-3-P1 (sodium salt)
Formal Name	1-(1,2-dioctanoylphosphatidyl)inositol-3-phosphate, disodium salt
Molecular Formula	C₂₅H₄₆O₁₆P₂ · 2Na
Formula Weight	710.6
Formulation	A lyophilized powder
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O[C@@H]1[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@@H](O)[C@H]1OP([O-])(OC[C@H](OC(CCCCCCC)=O)COC(CCCCCCC)=O)=O.[2Na]

Background Reading

Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36 481-509 (1996).

Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992).

PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt) is available in the following screening library:

Bio-active Lipid II Screening Library (96-Well)

Size	Price	Quantity	Subtotal
25 µg	$97.00		$0.00
50 µg	$184.00		$0.00
100 µg	$349.00		$0.00
250 µg	$776.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt)

PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt)

Description

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Downloads

Batch-specific Information

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PtdIns-(3)-P₁ (1,2-dioctanoyl) (sodium salt)