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PtdIns-(3,5)-P₂ (1,2-dihexanoyl) (sodium salt)

Cayman Chemical Item Number 10008396

Phosphatidyl-3,5-bisphosphate C-6 (sodium salt); DHPI-3,5-P₂ (sodium salt)

PtdIns-(3,5)-P2 (1,2-dihexanoyl) (sodium salt)

See more	Inositol Phosphates (78) Signal Transduction (314)

Description

PtdIns-(3,5)-P₂ (1,2-dihexanoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C₆:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and DAG stereochemistry as that of the natural compound. PtdIns-(3,5)-P₂ is rapidly synthesized from PtdIns-(3)-P₁ in yeast when a PtdIns-(3)-P₅-OH kinase is activated during hyperosmotic conditions.¹ PtdIns-(3,5)-P₂ is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.¹

1 Dove, S.K., Cooke, F.T., Douglas, M.R., et al. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390 187-192 (1997).

Synonyms	Phosphatidyl-3,5-bisphosphate C-6 (sodium salt) DHPI-3,5-P2 (sodium salt)
Formal Name	1-(1,2R-dihexanoylphosphatidyl)inositol-3,5-bisphosphate, trisodium salt
Molecular Formula	C₂₁H₃₈O₁₉P₃ · 3Na
Formula Weight	756.4
Formulation	A lyophilized powder
Purity	>98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O[C@@H]1[C@@H](OP([O-])(O)=O)[C@@H](O)[C@@H](OP([O-])(OC[C@H](OC(CCCCC)=O)COC(CCCCC)=O)=O)[C@H](O)[C@H]1OP([O-])(O)=O

Background Reading

Dove, S.K., Cooke, F.T., Douglas, M.R., et al. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390 187-192 (1997).

Size	Price	Quantity	Subtotal
100 µg	$39.00		$0.00
500 µg	$176.00		$0.00
1 mg	$312.00		$0.00
5 mg	$1,365.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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PtdIns-(3,5)-P2 (1,2-dihexanoyl) (sodium salt)

PtdIns-(3,5)-P2 (1,2-dihexanoyl) (sodium salt)

Description

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PtdIns-(3,5)-P₂ (1,2-dihexanoyl) (sodium salt)