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D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)

Cayman Chemical Item Number 10008442

1,3,4,6-IP4; Ins(1,3,4,6)-P4 (CAS 142507-74-2)

D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt) (CAS 142507-74-2)

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Description

The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol-1,2,3,4,6-pentaphosphate.1 These inositol pentaphosphates can be further phosphorylated to produce inositol-1,2,3,4,5,6-hexakisphosphate, or phytic acid, which serves diverse roles in eukaryotic tissues. Ins(1,3,4,6)-P4 is a poor activator of the inositol 1,4,5-trisphospate receptor in vitro.2 Other functions of this IP remain to be elucidated.

1 Raboy, V. Molecules of interest myo-inositol-1,2,3,4,5,6-hexakisphosphate. Phytochem 64 1033-1043 (2003).

2 Burford, N.T., Nahorski, S.R., Chung, S., et al. Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. Cell Calcium 21 301-310 (1997).

Synonyms
  • 1,3,4,6-IP4
  • Ins(1,3,4,6)-P4
Formal Name D-​myo-​inositol-​3,​4,​5,​6-​tetra(hydrogen phosphate),​ tetraammonium salt
CAS Number 142507-74-2
Molecular Formula C6H12O18P4 · 4NH4
Formula Weight 568.2
Formulation A lyophilized powder
Purity ≥95%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O[C@H]​1[C@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(O)​[C@@H]​(OP([O-]​)​(O)​=O)​[C@@H]​1OP([O-]​)​(O)​=O

Background Reading

Raboy, V. Molecules of interest myo-inositol-1,2,3,4,5,6-hexakisphosphate. Phytochem 64 1033-1043 (2003).

Burford, N.T., Nahorski, S.R., Chung, S., et al. Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. Cell Calcium 21 301-310 (1997).
Size Price Quantity Subtotal
100 µg $49.00 $0.00
500 µg $221.00 $0.00
1 mg $392.00 $0.00
5 mg $1,715.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-05-25. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt)
D-myo-Inositol-1,3,4,5,6-pentaphosphate (sodium salt)
D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
D-myo-Inositol-1,3,4-triphosphate (sodium salt)
D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt)
D-myo-Inositol-1,4,5-triphosphate (potassium salt)
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D-myo-Inositol-3-phosphate (sodium salt)
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