Cayman Chemical | 3-methoxy Limaprost | Description • 3-methoxy-2,3-dihydro-Limaprost; 3-methoxy-17α,20-dimethyl-Δ2-Prostaglandin E1

10008445 3-methoxy Limaprost

3-methoxy-2,3-dihydro-Limaprost; 3-methoxy-17α,20-dimethyl-Δ²-Prostaglandin E₁

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• See more Prostaglandins; Inflammation

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Limaprost is an analog of prostaglandin E₁ (PGE₁) with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an inhibitor of ADP and collagen-induced platelet aggregation and is 10-1,000 times more potent than PGE₁ as an inhibitor of platelet adhesiveness measured in vitro.¹ 3-methoxy Limaprost results from the Michael addition of methanol to the limaprost 2,3 double bond. The resulting novel compound is likely to retain FP receptor agonist activity; however there are no published studies of the pharmacological properties of 3-methoxy limaprost.

1 Tsuboi, T., Hatano, N., Nakatsuji, K., et al. Pharmacological evaluation of OP 1206, a prostaglandin E₁ derivative, as an antianginal agent. Arch Int Pharmacodyn 247 89-102 (1980).

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Purchase 10008445 3-methoxy Limaprost

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-18.
Prices are subject to change without notice.

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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.

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