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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt)

Cayman Chemical Item Number 10008452

1,2,4,5,6-IP5 (sodium salt); Ins(1,2,4,5,6)P5 (sodium salt)

D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt)

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Description

D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) (Ins(1,2,4,5,6)P5 (sodium salt)) is one of several different inositol oligophosphate isomers implicated in signal transduction. In human Jurkat T-lymphocytes, as well as in cytosolic extracts from fetal calf thymus, Ins(1,2,4,5,6)P5 (sodium salt) is phosphorylated by a 1/3 kinase to InsP6.1,2

1 Rudolf, M.T., Kaiser, T., Guse, A.H., et al. Synthesis and metabolism of the myo-inositol pentakisphosphates. Liebigs Ann 1861-1869 (1997).

2 Guse, A.H., and Emmrich, F. T-cell receptor-medicated metabolism of inositol polyphosphates in Jurkat T-lymphocytes. J Biol Chem 266(36) 24498-24502 (1991).

Synonyms
  • 1,2,4,5,6-IP5 (sodium salt)
  • Ins(1,2,4,5,6)P5 (sodium salt)
Formal Name D-​myo-​inositol-​1,​2,​4,​5,​6-​penta(hydrogen phosphate),​ pentasodium salt
Molecular Formula C6H12O21P5 · 5Na
Formula Weight 690.0
Formulation A lyophilized powder
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O[C@H]​1[C@@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(OP([O-]​)​(O)​=O)​[C@H]​(OP([O-]​)​(O)​=O)​[C@@H]​(OP([O-]​)​(O)​=O)​[C@@H]​1OP([O-]​)​(O)​=O.[5Na+]​

Background Reading

Rudolf, M.T., Kaiser, T., Guse, A.H., et al. Synthesis and metabolism of the myo-inositol pentakisphosphates. Liebigs Ann 1861-1869 (1997).

Guse, A.H., and Emmrich, F. T-cell receptor-medicated metabolism of inositol polyphosphates in Jurkat T-lymphocytes. J Biol Chem 266(36) 24498-24502 (1991).

D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) is available in the following screening library:

Size Price Quantity Subtotal
100 µg $110.00 $0.00
500 µg $495.00 $0.00
1 mg $880.00 $0.00
5 mg $3,850.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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D-myo-Inositol-2,3,4,5-tetraphosphate (ammonium salt)
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D-myo-Inositol-2,5,6-triphosphate (sodium salt)
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D-myo-Inositol-3-phosphate (sodium salt)
D-myo-Inositol-4,5-diphosphate (sodium salt)
D-myo-Inositol-4-phosphate (ammonium salt)
L-myo-Inositol-1,4,5-triphosphate (sodium salt)
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