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4-hydroxy Diclofenac

Cayman Chemical Item Number 10008518

(CAS 64118-84-9)

4-hydroxy Diclofenac (CAS 64118-84-9)

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Description

4-hydroxy Diclofenac is a CYP2C9 metabolite of diclofenac.1,2,3

1 Shimamoto, J., Ieiri, I., Urae, A., et al. Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9*3 allele. Eur J Clin Pharmacol 56 65-68 (2000).

2 Sawchuk, R.J., Maloney, J.A., Cartier, L.L., et al. Analysis of diclofenac and four of its metabolities in human urine by HPLC. Pharmacol Res 12 756-762 (1995).

3 Godbillon, J., Gauron, S., and Metayer, J.P. High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolities in biological fluids. J Chromatogr 27 151-159 (1985).

Formal Name 2-​[(2,​6-​dichloro-​4'-​hydroxyphenyl)amino]-​benzeneacetic acid
CAS Number 64118-84-9
Molecular Formula C14H11Cl2NO3
Formula Weight 312.2
Formulation A crystalline solid
Purity ≥97%
λmax 271 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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OC(=O)​Cc1ccccc1Nc1c(Cl)​cc(O)​cc1Cl

Background Reading

Shimamoto, J., Ieiri, I., Urae, A., et al. Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9*3 allele. Eur J Clin Pharmacol 56 65-68 (2000).

Sawchuk, R.J., Maloney, J.A., Cartier, L.L., et al. Analysis of diclofenac and four of its metabolities in human urine by HPLC. Pharmacol Res 12 756-762 (1995).

Godbillon, J., Gauron, S., and Metayer, J.P. High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolities in biological fluids. J Chromatogr 27 151-159 (1985).

Size Price Quantity Subtotal
5 mg $422.00 $0.00
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Cart Total $0.00

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Pricing updated 2012-05-25. Prices are subject to change without notice.

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