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Myristoleic Acid methyl ester

Cayman Chemical Item Number 10008581

(CAS 56219-06-8)

Myristoleic Acid methyl ester (CAS 56219-06-8)

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Description

Myristoleic acid is a cytotoxic component from the fruit extract of S. repens.1 It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively.1 Furthermore, myristoleic acid found in the by-products for making cheese is one of three fatty acids that are most active at inhibiting Candida albicans germination.2 It has a minimal inhibitory concentration (MIC) of 9 µM in vivo.3 Myristoleic acid methyl ester is a more hydrophobic form of the free acid.

1 Iguchi, K., Okumura, N., Usui, S., et al. Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells. Prostate 47 59-65 (2001).

2 Clément, M., Tremblay, J., Lange, M., et al. Whey-derived free fatty acids suppress the germination of Candida albicans in vitro. FEMS Yeast Res 7 276-285 (2007).

3 Umehara, T., Sudoh, M., Yasui, F., et al. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model. Biochem Biophys Res Commun 346 67-73 (2006).

Formal Name 9-​tetradecenoic acid,​ methyl ester
CAS Number 56219-06-8
Molecular Formula C15H28O2
Formula Weight 240.4
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCC/C=C\CCCCCCCC(OC)​=O

Background Reading

Iguchi, K., Okumura, N., Usui, S., et al. Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells. Prostate 47 59-65 (2001).

Clément, M., Tremblay, J., Lange, M., et al. Whey-derived free fatty acids suppress the germination of Candida albicans in vitro. FEMS Yeast Res 7 276-285 (2007).

Myristoleic Acid methyl ester is available in the following screening libraries:

Size Price Quantity Subtotal
50 mg $14.00 $0.00
100 mg $27.00 $0.00
500 mg $112.00 $0.00
1 g $196.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-05-25. Prices are subject to change without notice.

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