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15-keto Iloprost

Cayman Chemical Item Number 10008616

15-keto Iloprost

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Description

15-keto Iloprost is the C-15 oxidized derivative of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 15-keto iloprost.

1 Schrör, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) - equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol 316 252-255 (1981).

Formal Name 6,​9α-​methylene-​11α-​hydroxy-​15-​keto-​16-​methyl-​prosta-​5E,​13E-​dien-​18-​yn-​1-​oic acid
Molecular Formula C22H30O4
Formula Weight 358.5
Formulation A solution in methyl acetate
Purity ≥97%
λmax 236 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O[C@@H]​1C[C@H]​2[C@H]​(C/C(C2)​=C/CCCC(O)​=O)​[C@H]​1/C=C/C(C(C)​CC#CC)​=O

Background Reading

Schrör, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) - equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol 316 252-255 (1981).

15-keto Iloprost is available in the following screening library:

Size Price Quantity Subtotal
500 µg $107.00 $0.00
1 mg $203.00 $0.00
5 mg $856.00 $0.00
10 mg $1,498.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-25. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

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Iloprost

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