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3-(N-Maleimidopropionyl)-biocytin

Cayman Chemical Item Number 10008879

MPB (CAS 102849-12-7)

3-(N-Maleimidopropionyl)-biocytin (CAS 102849-12-7)

See more	Protein Binding (33)

Description

3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, etc.). MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range.¹ MPB can be utilized for cell sorting, enzyme immunoassay, protein blotting, and various cytochemical procedures.¹

1 Bayer, E.A., Zalis, M.G., and Wilchek, M. 3-(N-maleimido-propionyl) biocytin: A versatile thiol-specific biotinylating reagent. Anal Biochem 149 529-536 (1985).

Synonyms	MPB
Formal Name	N2-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-N6-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-1-oxopentyl]-L-lysine
CAS Number	102849-12-7
Molecular Formula	C₂₃H₃₃N₅O₇S
Formula Weight	523.6
Formulation	A crystalline solid
Purity	≥85%
λ_max	205 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard [H]N1[C@@]2([H])[C@@](CS[C@@H]2CCCCC(N([H])CCCCC(C(O)=O)N([H])C(CCN3C(C=CC3=O)=O)=O)=O)([H])N([H])C1=O

Background Reading

Ckless, K., Reynaert, N.L., Taatjes, D.J., et al. In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: Identification of Ran GTPase as a target for S-nitrosylation. Nitric Oxide 11 216-227 (2004).

3-(N-Maleimidopropionyl)-biocytin is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$11.00		$0.00
5 mg	$21.00		$0.00
10 mg	$37.00		$0.00
50 mg	$122.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Related Products

S-Nitrosylated Protein Detection Kit

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