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CAY10514

Cayman Chemical Item Number 10009017

Methyl-8-hydroxy-8-(2-pentyl-oxyphenyl)-oct-5-ynoate (CAS 868526-38-9)

CAY10514 (CAS 868526-38-9)

See more	Nuclear Receptors (86) PPAR (59) Atherosclerosis (323) Diabetes (134)

Description

CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC₅₀ values of 0.173 and 0.642 µM, respectively.¹

1 Caijo, F., Mosset, P., Grée, R., et al. Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors. Eur J Org Chem 2006(9) 2181-2196 (2006).

Synonyms	Methyl-8-hydroxy-8-(2-pentyl-oxyphenyl)-oct-5-ynoate
Formal Name	8-hydroxy-8-[2-(pentyloxy)phenyl]-5-octynoic acid, methyl ester
CAS Number	868526-38-9
Molecular Formula	C₂₀H₂₈O₄
Formula Weight	332.4
Formulation	A solution in methyl acetate
Purity	>98%
λ_max	220, 272 nm
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCOC1=CC=CC=C1C(O)CC#CCCCC(OC)=O

Background Reading

Caijo, F., Mosset, P., Grée, R., et al. Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors. Eur J Org Chem 2006(9) 2181-2196 (2006).

CAY10514 is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$19.00		$0.00
5 mg	$86.00		$0.00
10 mg	$152.00		$0.00
50 mg	$665.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

(±)8-HETE

8(S)-HETE

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